<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14044

Description Uncharacterized protein
SequenceMARPADPLDEQVSRRPDVLDWWMNHADPGLGFPRYPMEERLIHRYFSETPFFDWQTKEGLAITQAGNDWENFRRVHTRQEFEEILAKRAGTEYHVDGELVPIPGAPAMCKMSKNGVWVVRKIDRPESQERSNNPQNPFPETEVLGTYYIVGENVYMAPSIGDVVGNRLLSAATSLSTFFDKAKTLPSFSPTTGEGSVAPGADPMSLRAGSVAPESQADGTKTSSSAHDSRLLAQSLQMAIQFGEEYTDENPLLGEPGAFKFTSSTAAVKKRKADEEAAAQKAREAKAAAAASASNSPAGSPKLEAEKAAPTPPAVFTDAKASATEKVKKEERRKRKRRGGKSLGPSAKPTKQEQTKLPRIGQELQRDGEEAQDAEEEGESTSSVQKQSEPTTVDGSFARPMKTDSTSNQTEPAPEKESAETTEHVEEKNVEGVLDSVPDPAQYQEEQEGAKEASPTLDGRKPLEEDIPNMSEDEHMPPIRAPHIDPPRHVHHFDTYGLVNSLVDSGWDNAQAITIMKSVRLMMADNMDLAREALVSKSMVENETYLFRAACAELRTEVTTRRKAEQEKMRTERTHLQHEVDILGQRLGQESGAMKDELKGMFDDRKMAVRNEQREMESKVHQLNYKITVDLQADSRSEIEGLRWVMTRRVIIALGVVVVMVIGSLRLASTQVAKEQEEEKKRKAALKAKAKDSEERRNEFIGGGLPSEKGIDGGQILIKDGDNPSFVSLG
Length730
PositionHead
OrganismHortaea werneckii EXF-2000
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Teratosphaeriaceae> Hortaea.
Aromaticity0.05
Grand average of hydropathy-0.766
Instability index58.94
Isoelectric point5.36
Molecular weight80750.38
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
mitochondrion	GO:0005739	IEA:UniProtKB-KW

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14044
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     203.08|      54|      54|     347|     400|       1
---------------------------------------------------------------------------
  217-  284 (58.12/28.76)	ADGTKTSSSAHDSrlLAQSLQmaiQFGEEYTDENPlLGEpgafkftsSTAAVKKRKADEEAA......AQKARE
  290-  345 (57.68/28.49)	AASASNSPAGSPK..LEAEKA...APTPPAVFTDA.KAS........ATEKVKKEERRKRKRrggkslGP....
  347-  400 (87.28/46.87)	AKPTKQEQTKLPR..IGQELQ...RDGEEAQDAEE.EGE........STSSVQKQSEPTTVD......GSFARP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.98|      14|      17|     517|     533|       2
---------------------------------------------------------------------------
  517-  533 (19.63/18.40)	KSvrlMMADNMDLAREA
  537-  550 (24.35/13.90)	KS...MVENETYLFRAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.02|      38|     125|     463|     513|       3
---------------------------------------------------------------------------
  405-  442 (63.99/38.80)	STSNQTEP..APEKESAETTEHVEEKN.VEGVLDSVPDPAQ
  471-  511 (64.02/43.56)	SEDEHMPPirAPHIDPPRHVHHFDTYGlVNSLVDSGWDNAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.61|      16|      17|     613|     628|       8
---------------------------------------------------------------------------
  613-  628 (27.09/23.13)	QREMESKVHQLNYKIT
  632-  647 (27.52/23.63)	QADSRSEIEGLRWVMT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14044 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SPTTGEGSVAPGADPMSLRAGSVAPESQADGTKTSSSAHDSR
2) SSTAAVKKRKADEEAAAQKAREAKAAAAASASNSPAGSPKLEAEKAAPTPPAVFTDAKASATEKVKKEERRKRKRRGGKSLGPSAKPTKQEQTKLPRIGQELQRDGEEAQDAEEEGESTSSVQKQSEPTTVDGSFARPMKTDSTSNQTEPAPEKESAETTEHVEEKNVEGVLDSVPDPAQYQEEQEGAKEASPTLDGRKPLEEDIPNMSEDEHMPPIRAPHIDPPRHVHHFDT
189
263
230
495










Molecular Recognition Features






MoRF SequenceStartStop




1) AVFTDAKASATEKVKKEERRKRKRRGGKSL
2) GIDGGQILIKD
3) KQEQTKLPRIGQELQR
4) LKAKAKDSEERRNEFIGGGL
5) SPKLEAEKAA
314
710
351
686
300
343
720
366
705
309