<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14011

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPGQGMQPNPQQVATNQHQPGANQMVGQNPTHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRSIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGELERTEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length330
PositionHead
OrganismAnopheles quadriannulatus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-1.054
Instability index57.35
Isoelectric point9.08
Molecular weight37388.60
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP14011
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     261.17|      48|      49|      68|     115|       1
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    1-   62 (53.87/13.71)	MAGQFPgGYQS..PsghrgnynsP.I.IQQHLNQMNvPN............................QmGMMGFNQNNMMNSPQmqgvPGqGNQ
   63-  102 (80.72/25.31)	DMGLN..................PGM.MQQNQQQQQ.PG............................Q.GMQPNPQQVATNQHQ....PG.ANQ
  103-  151 (77.89/24.09)	MVGQNP.THQAAQP........sPQMgMQQQQQQQQ.QQ............................Q.QQQQQQQQQQSSNVG....PG..NP
  152-  225 (48.68/11.47)	MNNPQS.QNQSVPP.......nqPGA.GTAVQQQQK.AEfnllslcrigqetvqdivsrfqevfgilR.SIQP.PN..GTNQGQ....LS.SN.
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP14011 with Med30 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPGQGMQPNPQQVATNQHQPGANQMVGQNPTHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQ
1
175

Molecular Recognition Features

MoRF SequenceStartStop
NANANA