<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14005

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMASSSNVGSGNLVDELEEAFQSCIHALTKEESATGIDKDEIKVEVDQTTLKFIDLARQMEAFFLQKRFLLSALKPDLLLKEENFDLKQEIGRKDELIRKHYEKIESWKQLLSDQQNFNKPIQSMPPDMRGNLAGGAPGGGPAGMMASGGMNLPMQMQSQHQQQQMQQMQVQQQQMQMQQSMPMGASNAQMFQQGGIPRGVGQAGAGPGFPPGAGPNLQGPLAYLEKTASNIDLVGLGDGRR
Length241
PositionHead
OrganismAnopheles merus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.573
Instability index50.26
Isoelectric point5.30
Molecular weight26362.72
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14005
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.05|      44|      55|     108|     153|       1
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  108-  153 (78.37/34.72)	KQLLSDQQNFNKPiQSMP.....PDM..RGNLA.G.GAPGGGPaGMMASGGMNL..P
  166-  220 (64.69/23.28)	QQMQVQQQQMQMQ.QSMPmgasnAQMfqQGGIPrGvGQAGAGP.GFPPGAGPNLqgP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14005 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQNFNKPIQSMPPDMRGNLAGGAPGGGPAGMMASGGMNLPMQMQSQHQQQQMQQMQVQQQQMQMQQSMPMGASNAQMFQQGGIPRGVGQAGAGPGFPPGAGPNLQGPLAYL
114
224










Molecular Recognition Features






MoRF SequenceStartStop




NANANA