<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13957
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAEDGPLLNFFPDPPPFFKHFTTENLARLKEAESAVSSGDDAAHEDLSTGPKLSPEQILALPTELRYLIPPPPPSNDESFHVFGEPAKSSGNNNFTQTLEFISKTLGAQFVLSDWNYTQLYPSAASPSVEASSTAHSTDANIDRQQYLNRFNRSILLEYLSLLGILTLDPKSEHKDKKLKHILTLVCNMHALINEYRPHQARETLIGIMEEQVRRKKAEIEGIKAIEGKVVGVLDGFGMAVNSETEVENRDDAKNVSQKDAEEDKRKEAQRHLWDVVDDILAH |
Length | 283 |
Position | Middle |
Organism | Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Didymellaceae> Epicoccum.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.535 |
Instability index | 48.42 |
Isoelectric point | 5.11 |
Molecular weight | 31675.12 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13957
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 207.75| 51| 55| 57| 107| 1
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1- 55 (60.50/31.26) ..MAEDGPLLNFFP.DPPPffkhFTTENLARLkeAESA...VSSGDDAAHED..LSTGPKLSP
57- 107 (86.33/47.18) QILALPTELRYLIP.PPPP....SNDESFHVF..GEPA...KSSGNNNFTQT..LEFISKTLG
109- 164 (60.93/31.53) QFVLSDWNYTQLYPsAASP....SVEASSTAH..STDAnidRQQYLNRFNRSilLEYLS.LLG
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