<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13913
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MAASTNSNNADINLLNVEWRFHEWIMGVGGLNPDNVLDYFAQSPFWDPECNNAVLRMQTQFNNLGEMKQRLSEMTGVEFALVLERYPTLFVIQKQRRRSPHEVKPIAIYYVLQGSIYQCPDLQTLLSNRIVSFDPILYFISFFFFFFFFFLFASNVMPDFKYFLSLFFFFFFFFFFFFEF |
Length | 180 |
Position | Head |
Organism | Lobosporangium transversale |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mortierellomycotina>
Mortierellomycetes> Mortierellales> Mortierellaceae> Lobosporangium.
|
Aromaticity | 0.24 |
Grand average of hydropathy | 0.258 |
Instability index | 36.63 |
Isoelectric point | 5.10 |
Molecular weight | 21603.68 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | integral component of membrane GO:0016021 IEA:UniProtKB-KW
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13913
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 69.19| 15| 23| 138| 152| 1
---------------------------------------------------------------------------
138- 152 (36.51/10.42) YFIS.FFFFFFFFFLF
162- 177 (32.68/ 8.79) YFLSlFFFFFFFFFFF
---------------------------------------------------------------------------
|