Description | Mediator of RNA polymerase II transcription subunit 10 (Fragment) |
Sequence | LLEKLRDVTALFYELELRASDFGASSSNDQLFERINDLVSKYAELDDLQKAVDIDIPQDVLEYIEAGRNPTVYTRQFSEAVVRDNQYLNGKLQGYEDFASCLLDELQRQFPETKT |
Length | 115 |
Position | Middle |
Organism | Protomyces lactucaedebilis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Taphrinomycotina> Taphrinomycetes> Taphrinales> Protomycetaceae> Protomyces. |
Aromaticity | 0.10 |
Grand average of hydropathy | -0.508 |
Instability index | 38.47 |
Isoelectric point | 4.29 |
Molecular weight | 13274.55 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP13890 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 51.59| 16| 28| 1| 16| 1 --------------------------------------------------------------------------- 1- 16 (25.42/16.49) LLEKLRDVTALFYELE 31- 46 (26.17/17.15) LFERINDLVSKYAELD --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LLEKLRDVTALFYELELRASDFGA 2) LQGYEDFASCLLDELQRQF 3) SSNDQLFERINDLVSKYAELDDLQKAVDIDIPQDVLEYIEAGRNPTVYTRQFSEAVVRDNQYL | 1 92 26 | 24 110 88 |
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