<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13849

Description Uncharacterized protein
SequenceMSRTSSKRPLPTSANSGSSSAPSTTSHTFHPSPLDSLLSQNGLTRYHLQPPSWRAPWLPSKDKAGAAAGAEGGGLQAWPQFYPTCDGQEEDQLTEQAVKAGFSGRTVVQTETFSAHQLIYEKLKSNDILGNLARLASAVKKQQESNVPSYEPPNFRLPKRNTLSDSRRESWLADLANPAIPLSKLYSVIPNSARGVGLLELMWSRKVEVERAVWFVRASGAGEIQALARTRSPHLSTVITTFTTEWTSHVQEFVRKQLVEIAADVPSTNANSAGGARAGAPGAARIGTATMLGGVEGGKKAVLVDEELRKSWSIKFSWTLQLLSSLYDESLLSHSSFLRFLITQIESSTPSQLPFVLFLVEEYLAEFLQSEPMAARMVSACLGRVGELSPLPAPTAYQSSLHRTLTSLIRSTFLALPDAFVASPLWTSTTSPSQHVELEQLLMGVEEPKLRETVRVDWEELRGRQEAAGRGAAGEGEEGEAEGDEAEELETIQILDALTFPTSLSTSHKSLFRPPPPTRRRRLPLPSLLPLLFTWCTTPDRSGHHRRFAVSGLIKLELEEMRARGEEGVRGGEVERGFVEWVDALVLETPEEEKEEGEEDEEEEGGVEAEKERGNKREERVESVRRLLEELCRSGVVAFSLYLQRMIARGETEERGEGVTPSIHLTLLKTVPLYEDAGNPLAKRRVALRSSPSSRAETERLVQAAKNELFKLVPGIADEGWRAPIADSTPPAEQDCAPLLTSLSHLARDGTHLIIQRHVIPSGLARLFRPPGEHLALGVEESAVLVQTFLVTGDFWGLLQYLLLLLHHSPSRTLLIQILDVLQGDLDTWTSMGQLSVLASALFDAHKVLKTSGVGERRLIALLRQLGVAGHLDGEKVTLLEQDYQELVLSLSTSRPQAHGLPPGLPELQSLLVDSSPSAIAQLGTTLWYRYHSYDNWGIIAFDSAVQLLSAVSPNTIAVFLREINERLPTGLESQIGKWVKGLQVGVLVGTFGSKLGERLASLLGELVTEGVLSASGAVTGVLLPAWKSLLVEATSTTAAADTSESTDTPMFDPTLLQALETIASVFGSLLGDPTTHSSSSTTTLTPTLLITHQRSSSRRMSLYTHSSLADIGRCLALLVIQLELWTTSGHLERAHKTSALIQQVNACPSFQMAVARDPQTLATAMLDSEFVTSIPAITVYRPKLLAALLLTLKDGNTATPANLVSTEDWDLFLSGLTMWRLAVSKVEVQACLERLDLDNSLQDTEKAEALHTLSRHFLDRVCSGEGHTYLGEQVVKCYHGPASDELVSVAFTRLAEAVDGLAPTASPERRTHSLTTLRCTGRVLNTLLQSATAASRAEPLNLLLTAIKGCLDVLVEAEAEPAREAVLHAAHLLGIALRCSSKPASAETAELFKGCLILCAKLAASLAKDRWQESDLSSVLLDTCSHLLFGLTDMAPTARLPSLQTLLSSDLEIDALPDSTLSRLTRLFGPSSSLLPTLANPWELIEHADGGAPGAAAAAGAASTIAPSTIRSNIGPIDLALFDARVVQIIPKFTALDAQSTASSSTNGQTGPASSTAGTGISERGRQGNFDFETPCVGLSVAARDHRRTLTSARNHNLARYDPQAKTRKASAPAAAPSSTTELIIEDEPAPTMTKSGVKRKEHPEVVVIDSDDDDAPLATKPAAKKGKTSGKTTKGAARKKPKN
Length1685
PositionKinase
OrganismLeucosporidium creatinivorum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Leucosporidiales> Leucosporidium.
Aromaticity0.05
Grand average of hydropathy-0.153
Instability index48.11
Isoelectric point5.71
Molecular weight182001.31
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13849
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     168.75|      47|     116|     443|     490|       1
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  443-  489 (82.29/52.53)	MGVEEPKL..................RETVRVDWEELRGRQEAAGRGAAGEGEEG..EAE...GDEAEEL
  525-  587 (62.15/27.47)	LPSLLPLLftwcttpdrsghhrrfavSGLIKLELEEMRARGEEGVRG..GEVERG..FVE...WVDALVL
  588-  619 (24.31/ 9.89)	...........................ETPEEEKEE..........GEEDEEEEGgvEAEkerGNKREE.
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     700.12|     230|     466|     785|    1086|       2
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  819-  988 (194.86/170.50)	................................................................................................................LDVLQGDLDTWTSMGQLSVLASALFDAHKV...LKTSGVGER..RLIALLRQ..LGVAGHLDGekvTLLEQDYQE.............LVLSL.....STSRPQAHGLPPGLPELQSLL.....V...DSSP.SAIAQLGTTlwyryhsyDNWGIiaFDSAVQLLS.AVSPNTIAVFLREINerLPTGL.ESQIGKWVKGLQVGVL
  989- 1259 (305.22/209.74)	VGTFGSKLGERLASLL.G....ELVTEGVLSASGAVTGvLLPawksllveatsttaaADTSESTDTPmfdptlLQALETIASVFGSLLGDPTTHSSSSTTTLtptllithqrSSSRRMSLYTHSSLADIGRCLALLVIQLEL...WTTSGHLERahKTSALIQQ..VNACPSFQ....MAVARDPQT.............LATAMldsefVTSIPAITVYRPKL..LAALL.....LtlkDGNT.ATPANLVST........EDWDL..FLSGLTMWRlAVSKVEVQACLERLD..LDNSLqDTEKAEALHTLSRHFL
 1264- 1465 (200.03/107.16)	SGEGHTYLGEQVVKCYhGpasdELVSVAFTRLAEAVDG.LAP...............TASPERRTHS......LTTLRCTGRVLNTLLQSATAASRAEPLNL.........lLTAIKGCLDVLVEAEAEPAREAVLHAAHLLgiaLRCSSKPAS..AETAELFKgcLILCAKLAA...SLAKDRWQEsdlssvlldtcshLLFGL.....TDMAPTAR.....LPSLQTLLssdleI...DALPdSTLSRL...................................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.02|      34|     140|     159|     192|       3
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  159-  192 (59.05/42.14)	KRNTLSDSR.RESWLADLANPAIPLSKLY..SVIPNS
  299-  335 (48.97/33.40)	KKAVLVDEElRKSWSIKFSWTLQLLSSLYdeSLLSHS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.93|      26|      28|     720|     747|       4
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  720-  747 (43.11/29.14)	GWRAPIADSTPPAeqDCAPLLTSLS.HLA
  750-  776 (42.83/23.02)	GTHLIIQRHVIPS..GLARLFRPPGeHLA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.66|      50|     378|       1|      61|       5
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    1-   61 (80.66/53.98)	MSRTSSKRPLPTSANSGSSSAPSTTS...HTFHPSPlDSLLSQngltryhlqpPSWRAPWLPSK
  382-  434 (83.00/37.08)	LGRVGELSPLPAPTAYQSSLHRTLTSlirSTFLALP.DAFVAS..........PLWTSTTSPSQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13849 with Med12 domain of Kingdom Fungi
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