<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13833

Description Uncharacterized protein
SequenceMADLEEDPLSVSFKDTVFLEQCGLSYENALEYFRLSQFFDKTSINQQLIMQTKYNQLGTATMDASSLRGIEYALHSWSNMPSLYIIHKYFRHTREKTELLAVYYIAEGTIYQSPDLFTLLSNRILTSLHHVQHAFSTVSQESRFQPARPYHWGYEEEMNAEDDWVKSSADKHRNKRDAMNVDVNEDDDGIVIEAGGLEEEDEDEGVDVDEIVNLGETRGTSGTGAERKESYMKFRPLSATNYDGARAAYEFSARVDGLIEKMRASGPSWSTGGGFGSAGSGSSGVEAGSGGGGSGEGTSGVVGTGLTLEELKAAAKAKMEARAAAIQAANAVAGFKRPEPVDGGGYRAMPSAASGGTKKKKRMMSSSSMSESVGTPEYSGPSTTGLVPVQSPFVIRGSQSNVSSPFVKKGSGSGSKKKA
Length419
PositionHead
OrganismRhizoclosmatium globosum
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Chytridiomycetes> Chytridiales> Chytriomycetaceae> Rhizoclosmatium.
Aromaticity0.08
Grand average of hydropathy-0.522
Instability index47.33
Isoelectric point5.30
Molecular weight45138.48
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13833
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.11|      14|      14|     272|     285|       1
---------------------------------------------------------------------------
  272-  285 (27.61/11.95)	GGGFGSAGSGSSGV
  288-  301 (26.53/11.20)	GSGGGGSGEGTSGV
  343-  355 (19.98/ 6.66)	GGGYRAMPSAASG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.59|      14|      14|     186|     199|       2
---------------------------------------------------------------------------
  186-  199 (24.22/14.45)	DDDGI.VIEAGGLEE
  202-  216 (19.37/10.31)	EDEGVdVDEIVNLGE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13833 with Med6 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DGIVIEAGGLEEEDEDEGVDVDEIVNLGETRGTSGTGAERKESYMKF
2) KRPEPVDGGGYRAMPSAASGGTKKKKRMMSSSSMSESVGTPEYSGPSTTGLVPVQSPFV
3) MRASGPSWSTGGGFGSAGSGSSGVEAGSGGGGSGEGTSGVVGTGL
188
336
262
234
394
306

Molecular Recognition Features

MoRF SequenceStartStop
1) GGYRAMPSAASGGTKKKKRMMS
2) VGTPEYSGPSTTGLVPVQSPFVIRGSQSNVSSPFVKKGSGSGSKKKA
344
373
365
419