Description | Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MTIDYPSVIAALDTLAELSTCADSEDTSSRATEAITSLVHHQRTFLSFATSSLAPHQLRQRQLAAKEEEVAKEQARIQRLVDHLRSEQKRLEDVLAKAQAARLAKNNANNNMDNARIINYARRLAKFTSPPTNPNIPNINPPIPQDAHMKKSMLFAAHAVLAEATEDAAANDDEMDQTDDVFETDILEKLTRQAQPIEQEEEDNELNFDL |
Length | 210 |
Position | Middle |
Organism | Rhizoclosmatium globosum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Chytridiomycetes> Chytridiales> Chytriomycetaceae> Rhizoclosmatium. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.628 |
Instability index | 54.51 |
Isoelectric point | 4.81 |
Molecular weight | 23502.85 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP13831 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 50.31| 15| 22| 93| 114| 1 --------------------------------------------------------------------------- 100- 114 (27.26/23.03) AARLAKNNA...NNNMDN 121- 138 (23.05/ 6.18) ARRLAKFTSpptNPNIPN --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DNARIINYARRLAKFTS 2) ILEKLTRQAQPIEQEE | 113 186 | 129 201 |
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