<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13759
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSSSFYNSFSNFSSTTTTPNAQTTFTTSNSTLSDKMEYEKINENDNNNEISSNSSLLQIQKLNEIEKKIGTLLKVASQAISVLSGDVDDNIKNNFEELSIQYLELVNDIQLGLRETFRFLTNTDIESTSYTANLPYISNTYGEEKDHEISVKVLELVKTKINSILNSMGGSTIPLPISLSSSSIASGTPNHLMPAGLNHKFLNSRFTTNAELIASSLCSSNNNSNANIKMDDELANDIAISKKQKIKKEVEDLMEVEKDTRDNKVIEQDINEQVNPTIDDITLNSENKKETVKPSDFITNNYLNIENNNNTSSDKPEIQDLDLDF |
Length | 325 |
Position | Head |
Organism | Anaeromyces robustus |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Chytridiomycota>
Chytridiomycota incertae sedis> Neocallimastigomycetes> Neocallimastigales>
Neocallimastigaceae> Anaeromyces.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.598 |
Instability index | 39.50 |
Isoelectric point | 4.52 |
Molecular weight | 36238.58 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13759
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 70.45| 22| 86| 112| 133| 1
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112- 133 (39.64/23.47) GLRETF...RFLTNTD.IESTSYTAN
196- 221 (30.82/16.89) GLNHKFlnsRFTTNAElIASSLCSSN
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 127.59| 41| 259| 15| 63| 2
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15- 63 (57.81/37.10) TTTTPNAQTTFTTSNSTLSDKMEYEkinendNNNEISSNSSllQIQKLN
282- 322 (69.77/30.26) TLNSENKKETVKPSDFITNNYLNIE......NNNNTSSDKP..EIQDLD
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