<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13737

Description Uncharacterized protein
SequenceMNSAGGSSQQGTGTRPSLSSTPASGLGRARLERPGWRGGNDIQPLNKYTPTPTSGTVPLHSSQDIGYTDFRPTRPGQSEDILNEHTIRYGYTDVPRVENEFVSQHEMVYDRLMDTRVFQDLQAFAAGVAQRQLARGSVGSLALPRLPNRPVRSDEQREEWLRNLANPRLPLNVLINTMPFGHRGERLLESLKQHRVPLLRAVWAIRLTGVYEMFGQQARTLDHAGLKALEQSYTLQWSKAVTQFLEHTLSAAPTGDHDAAQVKKWSQDWTYSLSLLHVQADQGLMDQRHLVSWLASQFRQLPVDKCMLVLPVIKDYVPEISKSRTPLRKLIQAVAFRVEQAQRYPSLAQFGKTVCGFLVELFEKFPDAFVEPTTWWDGYRTPLYVACDKCDRVDRRRMKQMLAHVDERNAKFSSLAPLTVVTAKDGTGCEVGGSAQILQVLNEITIDIGVSTVFSSVFEGAKAASEVIDAHKIRIICYWAVDSSISSTATQFRTMFGTRLIQLHKEQLPPDTPTSALQSAIVSFLDIFTPPDPHADNERYVWRVCLLLERLSYANCFSVPKYLQLLTARGDFFGANVTTVKSQRHLAYAKGLAVGSPADDEQRQMLLYGFDMDLERAAQNESDGAVCASLRREISRILPFLVAYTCATPLRAKANGKEPTIDAALAMWWRGSGPSSSILDPQNLPTPEQLAGVSLSAPSSRASCVKDWISPLSDHISDESLLGQDISAECLGLLSKSSRNILDMVVHQRLMPIVYDFVVKDIKVGVDNWRVITQPGTSLLNARQTAAIIRVLSVSGMFAHMLDFLLWLISHSKATPVLATVHTALVRFTDAWRLLGRLTEAAIAVGNIYTENSSSSSVDLESFKTLSYWSTVDPADTQISALAQKAHSDHDAYVDMQTQSLLLPSHAAGPVHTDKELMQLAQRVVSERQRENAQSSDETDWTVTQCFDKLSRWAASQMAKSDFGSPPGLQPNGVISSPVMGSKSRSAKLESENALMECFLDLAAQYVGWFSDNSGLLVTPHTTSQLLLTALSTAINAWPIARNSAAAHVAVPVSSTAGGSPAVQPTESPSPSPLFAVADIDRAMLVTSAWVTKLLASGCLRISYLVPWLIEELRSDVLQTPAAKYACLAGIVNTLSVSPDQIILHRPPLVRADSRAGSLQTSAQHPAHRLTDRLIIDSCWDSTLIANKVSRIQTVELVFTCASTGGQLRDSGMPQLETILVHAATELAQSVWVQMFIDFIPLSQQDASSKTVRGQHYNMLEIYRANIEVQIRSPAVSLPVKRAVLRSLLTLCEGNDPASEGFSAMTTPEVALRLRETLNRFWFGPAARGKATPAAFKCATILNSLMLFSATALQETEATTDAFAVAAGAATMASAAHSASEPANALQDIDTLSQTLGRGSGQVQFVTNPTTFLASCVLEAVFSWGTPGRDAKNMDSKRYASLAEVLSTLDPTTLLQQTEACWATLFRLNTPLLRATSDQTGPHSSEGSPIQRSRSNQQDQSPSAKAALAIIRSVQQSVPTLTSPDAFGDIDGQLMLTLATHAEKQGSRKEGAPVDSAFAPGTLLSSVRAIACGLIGQLQAISAHASSDVASTLHQRQVPPSRLTTPPAQPQDTEKLQPVDPQRLCLAIRWRLQALQPMCGLMRAHPEEFAADEWLMTLVTLCLSPLCQSAANGRDSRFLPGITAAMRKRSLVLLRRVAPLPSPAHTPGLDNPWIWVEALEFTPLSNLSPATPINMGLEGMTPFTLRGALEAEEAKKGVKRPADAANRMQFLDNPYYPKQPAFMAPLADTPIPWQTRLVWRNQCQQAFGENGA
Length1812
PositionKinase
OrganismLinderina pennispora
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Zoopagomycota> Kickxellomycotina> Kickxellomycetes> Kickxellales> Kickxellaceae> Linderina.
Aromaticity0.07
Grand average of hydropathy-0.145
Instability index46.63
Isoelectric point6.79
Molecular weight198240.56
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13737
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     225.13|      79|     631|      36|     292|       1
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  204-  292 (109.30/179.18)	AIRLTGVYEMfGQQARTLDHAGLKALeqSYtlqWS...KAVTQFleHTLSAAPTGDHDAaQVKKWSQDWTY.SLSLLHVQADQGLMD..QRhLVS
  842-  926 (115.82/52.75)	AIAVGNIYTE.NSSSSSVDLESFKTL..SY...WStvdPADTQI..SALAQKAHSDHDA.YVDMQTQSLLLpSHAAGPVHTDKELMQlaQR.VVS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     303.37|      98|     274|    1155|    1334|       2
---------------------------------------------------------------------------
 1215- 1316 (158.67/214.98)	QLETILVHAATELAQSVWVQMF....IDFIPLSQQDASS.KTVRGQHYNMLEIYRanieVQIRSPAVSL....PVKRAV...LRSLLTLCEG..NDPASEGFSAMTTPEVALRLRE
 1577- 1688 (144.69/64.79)	QLQAISAHASSDVASTLHQRQVppsrLTTPPAQPQDTEKlQPVDPQRLCLAIRWR....LQALQPMCGLmrahPEEFAAdewLMTLVTLCLSplCQSAANGRDSRFLPGITAAMRK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.99|      11|      20|      40|      51|       3
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   40-   51 (16.61/14.42)	NDIqPLNKYTPT
   63-   73 (21.38/13.01)	QDI.GYTDFRPT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.54|      22|     631|     817|     838|       4
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  817-  838 (39.49/24.59)	VLATVH.TALVRFTDA.WRLLGRL
 1445- 1468 (30.05/16.81)	VLSTLDpTTLLQQTEAcWATLFRL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.04|      47|     358|    1362|    1426|       6
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  410-  458 (72.79/34.04)	AKFSSLAPLTVVTAKDGTGCEVG.GSAQILQVLNEITidIGVSTVFSSVF
 1375- 1422 (75.26/47.19)	AAHSASEPANALQDIDTLSQTLGrGSGQVQFVTNPTT..FLASCVLEAVF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.67|      28|    1013|     681|     714|      12
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  681-  714 (35.18/30.54)	PqnLPTPEQLAGvsLSAPSSRASCVKdwISPLSD
 1699- 1726 (55.49/26.53)	P..LPSPAHTPG..LDNPWIWVEALE..FTPLSN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     255.68|      63|     956|     139|     201|      15
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  139-  201 (107.25/62.62)	GSLALPRLPNRPVRSDEQR....EEWLRNL.AN..PRLPLNVLINTMPFGHRGERLLESLKQHRVPLLRA
 1098- 1152 (90.75/51.75)	GCLRISYLV..PWLIEELR....SDVLQTP.AA..KYACLAGIVNTLSVSP......DQIILHRPPLVRA
 1155- 1211 (57.68/29.97)	RAGSLQTSAQHPAHRLTDRliidSCWDSTLiANkvSRIQTVELVFT..CASTGGQLRDS...........
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13737 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MNSAGGSSQQGTGTRPSLSSTPASGLGRARLERPGWRGGNDIQPLNKYTPTPTSGTVPLHSSQDIGYTDFRPTRPGQSEDILNEHTIRY
1
89










Molecular Recognition Features






MoRF SequenceStartStop




1) RARLE
28
32