<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13733

Description Uncharacterized protein (Fragment)
SequenceMRNNSLGHSNLNPNYHRHNPGSINGVGNNNINNSNNVMGMNVGNGYNVNGMGYSSFKGGNSSHSRTASASSVSMPYSSNYSKSSNYYSNNFTARPVKRYRIQPPEDKLIHKTRQLGYFGYSLQQKDQPEDIFNEKTINSGYINIPIIDIKSETFTDRNEMVEKLKNNKYLSLLGSFAEEIIVEKQKQSHNKSLVSIIKNDSNENDEIMNSRMQISNIKQAVNLILSQNLSLFDSVRLIADLKDACKNKLFTEWSQSVMEELIKFPNFDVLQQNLNNNSSNNSDSNQKNNSINEQIIKKWDYCVTLTRYLYIEGLIEPRILLKGLLNIFDSSNFQQCVLFLPILKEYLNDFSRSRALMTTLLDTCLKKLNNIKEEYLNKKIIEYHYINLISLVKQILIATPDVMVKPSTWKSLEKVLNNRFIVYYPNNMNSSIKTAYENLFQTYQQMITKRNLLFINYSFDTTLMNKSEINNIDEAPMNYFENCSDFTELCKLINLKIFYNDDERNKNELVFDEPISLEKKIFILCYWGIKFHKHGPYIVSILIKKLVETSNNSDEEVEKLQNIFSKILDEFDIENKFAYKNLIELFGELIRKELFFSNQYIRKLIARGYFEKNKINEKNTKRYLRYLYDFPVFEINTEQINQRRILLYSLYQSSKEAKEIKVFNKVKELIKLRLPYIFNSDLTNEKNVKSYYDKPEDYENLATFNIDDKIYKILSNISSYWKYKISEWLKNVVYNYLVPNIPIGNDNWWYINPGDSLLNVRQFATIIQILEIINDKTGIIDLCLWLIPKIKKRTMYHYIISCINKNKLLITLTRRQKELFDIIWNKHNTLKRENNIDRILLLFLKSLHGTPGFKIEKDILEQIENDLVINYKEYIDYEDVITTFENTINSIKDYNTITSSDLLLLQYKYQHNITELKKYFKYILEIKIDRDYSRMNKNQIIYNFDIFTEILRQFNNGFEDFDDVIFEYLSESYLKDALVNVSNNQQISYQANSVMKKINFKLQNYFFVLLFTSGGCSLLRLLLEYIKPVMELFQEHLINGKSINENSIILFDNVITLMHILFTVDDSRPVIDDLYLTTKIIHYLRSRRINILTKDKAYNTCLELLQITITIFSELIIKSQSTLSKQFLPKIKIFLNDWIKSQWFFKINLININYMYKKLFTFNVIYPDSIMKAVNYLLALYLLNIINEGIYYTTGKRIESPILNISNIENNKEFKIENVKCEEWENLFENIYLIYKNWSPNVCKTALIITINKLWLIDDKTKSKLDEDSNSYSFTKGFINATLKILTSIHDNKSTSSIIDNECISHKTLLSYISLFKPKFNVEITRLIINSFYLNYESPLEICINKKSQLQFNTIKYFSDFFSAVIHSINIAKKNFDPNNNNNANHMLGINDVTIYNIIQKLLKHFQWYNDNKKEFEIMEDYQILYDEAKYIIGNNLVDEISIFNKKKLLRSIQPIKEDHKHLTIEIFRSNIFLMLKIIQPLLTSICKRPKEGKLLSWIKVLIHLLSSHIIHGNGVQLKLFEFTLDLVTFLLDETPDDIKKDQFSLIQEIQKEIDIPPILSSRINQILPIRIQNIYEFNLSISGNNNSKLITTNIINPWDWFRETKPNPSDQNNDKKDDNRNNGLILKNVPLNSINFQKDKIYPLSFFNINKFKKLEKGLMTTYETHFDDFIT
Length1673
PositionKinase
OrganismAnaeromyces robustus
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Neocallimastigomycetes> Neocallimastigales> Neocallimastigaceae> Anaeromyces.
Aromaticity0.12
Grand average of hydropathy-0.347
Instability index42.82
Isoelectric point8.70
Molecular weight197306.62
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13733
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.69|      16|      21|     610|     628|       1
---------------------------------------------------------------------------
  610-  626 (25.70/11.21)	FEKNkINEKNTKRYLRY
  633-  648 (26.99/10.82)	FEIN.TEQINQRRILLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     742.26|     149|     149|     309|     457|       2
---------------------------------------------------------------------------
  309-  455 (235.27/118.95)	..............L.YI.EGLIE...PRILLKGL...........LNIFDS.SN...FQQCVLFLPI.....LKEY..LNDFSR.SRALMTTLLDTCLKKLNNIKEE..YLNKKI.......IEYH....YINLISLVKQ.I..LIATP........D...VM...VKPSTWKSLEK.V..LNNRFIVYY.......................P..NN..MNSSI.K..T.AYENLFQTYQQMI.........TKRNLLFI
  456-  595 (124.89/59.43)	NY.................................sfdttlmnkseINNIDE.APmnyFENCSDFTELcklinLKIF..YNDDER..............NKNELVFDEpiSLEKKIfilcywgIKFHkhgpYI..VSILIK.K..LVETS........N..............NSDEE.VekLQNIFSKIL..........................DE..FDIEN.K..F.AYKNLIELFGELI.........RKE..LF.
  747-  905 (128.32/61.28)	NW............W.YI.............................NPGDSlLN...VRQ...FATI.....IQILeiIND.K.......TGIIDLCLWLIPKIKKR..TMYH.................YI..ISCINKnK..LLITLtrrqkelfD...II..wNKHNTLKR.E......NNI.DRILllflkslhgtpgfkiekdileqiE..ND..LVINY.KeyI.DYEDVITTFENTInsikdyntiTSSDLLLL
  906- 1062 (159.80/78.26)	QYkyqhnitelkkyFkYIlEIKIDrdySRMNKNQI...........IYN.........FD...IFTEI.....LRQF..NNGFEDfDDVIFEYLSESYL.KDALV..N..VSNNQQ.......ISYQ.......ANSVMKK.I..NFKLQ........NyffVL...LFTSGGCSLLR.L..LLEYIKPVM.......................ElfQE..HLING.K..S.INENSIILFDNVI.........TLMHILF.
 1127- 1229 (93.98/42.77)	................................................................FLPK.....IKIF..LNDWIK.SQWFF.........KINLININ..YMYKKL.......FTFN....VIYPDSIMKA.VnyLLALY......llN...IInegIYYTTGKRIESpI..L.NI.SNI........................E..NNkeFKIENvK..CeEWENLFE.......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.68|      19|      23|       7|      27|       3
---------------------------------------------------------------------------
    9-   27 (37.95/27.32)	SNLN..PNYHRHNPG...SINGVG
   29-   52 (26.73/ 9.93)	NNINnsNNVMGMNVGngyNVNGMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.36|      14|      23|     104|     117|       4
---------------------------------------------------------------------------
  104-  117 (26.61/20.71)	PEDKLIHKTRQLGY
  128-  141 (26.74/20.85)	PEDIFNEKTINSGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     481.56|     141|     201|    1249|    1449|       5
---------------------------------------------------------------------------
  167-  281 (99.94/36.13)	...............................NKYLSL....LGSFAEeiivekqkqshNKSLVSIIKNDSNEND..EIMNsrmQISNI..........KQAVNLILSQnLSLfD..SVRLIADLK.DACKNKlfteWSQSVMEELIKFPNF........DVLQQNLNNNSSNN..............
 1249- 1397 (224.57/196.34)	ITINKlwlIDDKTKSKLDEDSNSYSFTkgfiNATLKI....LTSIHD...........NKSTSSIIDNECISHK..TLLS...YISLF..........KPKFNVEITR.LII.N..SFYLNYESPLEICINK....KSQLQFNTIKYFSDFFSaVIHSINIAKKNFDPNNNNNANHMLGINDVTIYN
 1451- 1577 (157.04/68.98)	RSIQP...IKEDHKHLTIEIFRSNIFL......MLKIiqplLTSI........................CKRPKegKLLS...WIKVLihllsshiihGNGVQLKLFE.FTL.DlvTFLLD.ETPDDI...K....KDQ............FS.LIQEIQ.KEIDIPPILSSRINQILPIRIQNIYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.30|      15|      27|     678|     692|       8
---------------------------------------------------------------------------
  678-  692 (27.77/13.11)	FNSDLTNEK...NVKSYY
  704-  721 (24.53/10.70)	FNIDDKIYKilsNISSYW
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13733 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MRNNSLGHSNLNPNYHRHNPGSINGVGNNNINNSNNVMGMN
1
41










Molecular Recognition Features






MoRF SequenceStartStop




1) NPWDW
1597
1601