<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13701

Description Uncharacterized protein
SequenceMPPQPLTSEAGPSTDLFVEDFGPPIWRTVLNKRADLGYPDFYPSRPGFGQPEDILTEENVKNGYSARPFVTVTSAESFSMHGPIHNQLVNGCLATLNKLGREIIEKRDECMPQFGERAFRIPVRVTYNDVKRTQFLSDLANPNVPLYKLMRNPIPHGFKGLELLDTMFSPSFVPAHNRSISGPQASALPQSIAIDRAVWFIRVLGSNEISAHRGRAQPVSAPSAPSPAAAVTPSSSLSQNTSVALPLSSSDWHTQEFTTLYTNWLRIQLGQLSLPTVQTRGVPAPRSGATSVLGDEKARARWLVKWNYSLALLRQLFNRHLISARVLGAWLVDMLASSNLAQLGFVARLAADHITALARHVHIARPCLRAACDRIVEIREAKMPLENVEMVLKSLIQVLCRCDEMALMNPSLWRKHRDLILSLVNPSPSIASLEERSKVLMFKPPSTGSLSTPRRQQMEDLQKLDSMNAETNMLQLCLSYFDGNASPTSSTLDVGRFDEKVVVLLNWAMGSFQLGIHRAYAVHTLLVMWREKFDEHQSKATRSAAMDFFPTLYQWLDTSEAAKSRQNAQAIGITFGELTRQGLFSYGRYLQTLIAQGHSARFDLSASSHHLRILRSLPIFVQGKDLLHQRRLALTGGNKQLLAMHETEEKEIMAEFEEECKEFVPEVFGYKRYGASTQYKEAVYHHLRSTNKITRHLFLQARFWIYPLAVSSLVIQGRRPAIDASAFARILHVFRECNGYSTMADYLVKALQINRDIDILDCIIDTIRRDADVWTAMDRWELLTDALMERNAAQDTAGQHHAALASLLVELARRDRLSAEDLAEVQSSIDSHRKARPDPSTTFFDGAQSMDGVRQVMAKGDVTAASLLGAKLFVRHGPFENWSTLWWETLVDAIQTSTHATIVDAVTAQIATVFEQAEGQLDSVVDAWLQTVTNPIELLSNGSHLCTILLHECAHRHLRLVSRTLETLVYPVWAKCAAATLKDGSCSHPLSVTNSVTLCQQLLLTKPPNQSLPPTSLRQALVLQTERGETLKGAHVISLLQHLPFLVILEKGSATPERLQTQISLLLEQLAATPHFKAAAFRHLDVLKDAFLSNEWSESSMENLEAGMVDVLKMIMSQGTNNDIASLESSPRSSAWRWTSIVLSMRVDFKRLAMRINSDGDTSEAKTTLSQLVRSNLDRDMSADDADLLCEAIRGIERVVAQEIISFGIERLGALLAQVIDADSQAQTDHPCKSIDLLLRVLDSASRTSPLPWGDHAILTARHALLDLISVALQSIERQFASDESELPGDDPPKSSELLHVAFRLLRFSLGLPIVESPNPTLPRPDFGRLATAFARLLSALPTSIGDRATIRLGDMLAYILDSAPSRATVHSALVAEVSLHQSKASILQALSILSIRHRPTALNLGDDTVPLDDRPWELFERLDPKPRRAKGQDFYLASKKYKDTAAISMALFAPRIEYDAMPRDEEDDDAASEASDPDLYASERDLGNDLAGESSMLKQFTTAIYGGPEEASIEDDIVIHHASPTTSVSSPSNLLRPRRASTRGMPTGSDKDPIPLVDDDDDDDDDDDSGSEEDEPELLPPRGKRPRVASKSTGSVGGKTTRKTTGGKM
Length1610
PositionKinase
OrganismKockovaella imperatae
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cuniculitremaceae> Kockovaella.
Aromaticity0.06
Grand average of hydropathy-0.224
Instability index48.81
Isoelectric point5.97
Molecular weight178400.87
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13701
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     210.98|      53|      58|     214|     270|       1
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  169-  205 (47.66/24.39)	.........SPSFVPAHNRSISGPQASALPQSiAIDRAV.........WF...IRVLG
  218-  270 (91.11/61.95)	P.VSAPSAPSPAAAVTPSSSLSQNTSVALPLS.SSDWHTQEFTTLYTNWL...RIQLG
  275-  328 (72.21/39.10)	PtVQTRGVPAPRSGAT..SVLGDEKARARWLV.KWNYSLALLRQLFNRHLisaRV.LG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     171.84|      47|      59|    1432|    1490|       2
---------------------------------------------------------------------------
 1443- 1487 (66.99/65.39)	...KDT.AAISMAL..FAPRIEYDAmPRDE..EDDDAASEASDPDLYASERDL
 1488- 1535 (58.11/36.50)	GND...lAGESSMLkqFTTAI.YGG.PEEAsiEDDIVIHHASPTTSVSSPSNL
 1549- 1579 (46.74/27.62)	GSDKDP...........IPLVDDD..DDDD..DDDDSGSEEDEPEL.......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.56|      26|      59|    1342|    1368|       3
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 1342- 1368 (42.99/33.99)	PT..SIGDrATIRLGD...MLAYILDSAPSRA
 1400- 1430 (39.57/25.53)	PTalNLGD.DTVPLDDrpwELFERLDPKPRRA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.76|      21|      59|    1218|    1238|       4
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 1218- 1238 (37.50/23.33)	QVIDADSQAQTDHPCKSIDLL
 1279- 1299 (37.25/23.12)	QFASDESELPGDDPPKSSELL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     347.12|     114|     140|     724|     849|       5
---------------------------------------------------------------------------
  724-  849 (176.93/129.83)	ASAFARILHVFREC.NGYSTM.ADYLVKALQINRDIDILDCI...IDTIRRDAD..VWTAMDRW.ELLTDALmernaAQDTAGQHHAALasLLVELARRD.RLSAEDLAEVQSSIDSHRKArpdpsTTFFDGAQS
  865-  987 (170.19/100.28)	ASLLGAKLFVRHGPfENWSTLwWETLVDAIQTSTHATIVDAVtaqIATVFEQAEgqLDSVVDAWlQTVTNPI.....ELLSNGSHLCTI..LLHECAHRHlRLVSRTLETLVYPVWAKCAA.....ATLKDGSCS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.35|      31|      59|     399|     434|       7
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  399-  434 (48.88/38.85)	LCRCDEMALMNPSLwrkhrDLILSLV..NPSPSIASLE
  461-  493 (49.47/27.11)	LQKLDSMNAETNML.....QLCLSYFdgNASPTSSTLD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.89|      47|     638|     521|     582|       9
---------------------------------------------------------------------------
  521-  582 (61.30/73.96)	AVHTLLVMWREKFDEHQSkatrSAAMDFFptlyqwldtSEAAKS..RQNAQAIgITFGeLTRQG
 1165- 1213 (74.59/46.10)	AKTTLSQLVRSNLDRDMS....ADDADLL.........CEAIRGieRVVAQEI.ISFG.IERLG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13701 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LKQFTTAIYGGPEEASIEDDIVIHHASPTTSVSSPSNLLRPRRASTRGMPTGSDKDPIPLVDDDDDDDDDDDSGSEEDEPELLPPRGKRPRVASKSTGSVGGKTTRKTTGGKM
2) YDAMPRDEEDDDAASEASDPDLYASERDLGN
1498
1459
1610
1489










Molecular Recognition Features






MoRF SequenceStartStop




1) DDDSGSEEDEPELLPPRGKRPRVASKSTG
2) KDPIPLVDDDDDDD
1567
1552
1595
1565