<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13686

Description Serine Threonine protein kinase
SequenceMAAPEEVKKVLVALKNNKDTECKAALHWAITTFIKPGVDEAVLGHVLKFPDLIPTAMGRVPFAWAEDKFQNAYLKVDTEKAGIFLKDYQEVCKEKKVTASFMVRWCDDRESGILSLVEETGATHLVMGTGSTKSKFTTLLKGKSLTARVAKHARCSVYLINNRAELVTSHIYDGKRGAAGSGAANGSQSDGSSSSTPSPTASPSSVLPPVLPPIPLSPLPRNETVTVPHTPPATPAVAIPSAPVLPPGDYSHPWGSIPSPHSQPSSSPRSLYSEPGPSPQGGLQPPNLYAQSYSGYIITESGSFLPAPRTSANGHAGPQNGSRFERADMATGPQVWVNSDGQQLSGDEPEFQIYEERQRERGGQSPASNGPAKARFDNGELAEVLRKLKMSEEATARLQAQQADYERQLREAESRALSANSLAEAERARALAAHQERELAKQESALARRAEQEARNKERAAQEAAERERQERVAERQQAAEHYKELLERQKAQRQYRTYSFRELEAATESFSPAKLLGEGGFGQVYLGRLEHTPAAIKILNPEGLQGPDEFKREVEILSGLRHPHIVMLMGCCPERGCLVYEYCANGSLEDRLARKGDSAALPWFTRIRIAFEVAVALLYMHTSRPSIIHKDLKPSNILLDQNLTSKLGDVGIASVAPELATATFTGMTRRRGGGRQAQTSIFDSSPQGTPMYIDPEYQQKGTFNQKSDVYAFGICLLQLLTNRPPLGIVGAVEDALDEGNVLPVVDQTAGSWPEEVATKIANLGLKCAEIRRRDRPDLEKEVLPVLEAARTLAMEAAAREASQGLNQGATPEATGEEDVVPSIFLCPISHDIMEDPVVAADGNTYERAEIARWFQRKRTSPLTNVPVTNLLLTPNLIIRSAIKEWQEGNRRSMSRGFTGAGARSRGG
Length908
PositionTail
OrganismKlebsormidium nitens (Green alga) (Ulothrix nitens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Klebsormidiophyceae> Klebsormidiales> Klebsormidiaceae> Klebsormidium.
Aromaticity0.06
Grand average of hydropathy-0.477
Instability index52.15
Isoelectric point6.55
Molecular weight98998.49
Publications
PubMed=24865297

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13686
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.75|      23|      31|     199|     229|       1
---------------------------------------------------------------------------
  199-  221 (45.48/16.82)	PTASPSSVLP..PVLPPIPLS......PLPR
  231-  260 (29.28/17.87)	PPATPAVAIPsaPVLPPGDYShpwgsiPSP.
  261-  280 (33.00/11.43)	.HSQPSSS.P..RSLYSEP.G......PSPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.42|      39|      39|     398|     436|       2
---------------------------------------------------------------------------
  354-  391 (22.50/ 6.96)	.......YEERQ.RERGGQSPASNGpakarfdngeLAEVLRKLKMS....
  398-  436 (58.96/28.94)	LQAQQADYERQL.REAESRALSANS..........LAEAERARALAAHQE
  439-  478 (50.96/24.11)	LAKQESALARRAeQEARNKERAAQE..........AAERERQERVAERQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.35|      28|      29|     506|     534|       3
---------------------------------------------------------------------------
  506-  534 (46.17/26.65)	AATESFSPAKLLGEGGFG.QV.YLGRLEHtP
  535-  564 (41.19/19.68)	AAIKILNPEGLQGPDEFKrEVeILSGLRH.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.45|      10|     231|     665|     674|       4
---------------------------------------------------------------------------
  665-  674 (21.59/14.65)	FTGM.TRRRGG
  898-  908 (15.85/ 8.41)	FTGAgARSRGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.68|      21|      37|      28|      48|       5
---------------------------------------------------------------------------
   28-   48 (37.45/24.00)	WAITTFIKP..GVDEAVLGHVLK
   64-   86 (32.23/19.72)	WAEDKFQNAylKVDTEKAGIFLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.13|      40|     103|     612|     651|       6
---------------------------------------------------------------------------
  612-  651 (67.49/42.15)	FEVAVALLYMHTSRPSI.....IHKDLKPSNIL..LDQNLTSKLGDV
  711-  757 (59.64/36.44)	YAFGICLLQLLTNRPPLgivgaVEDALDEGNVLpvVDQTAGSWPEEV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13686 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESGSFLPAPRTSANGHAGPQNGSRFERADMATGPQVWVNSDGQQLSGDEPEFQIYEERQRERGGQSPASNGPAKARFDNGELAEVLRKLKMSEEATARLQAQQADYERQLREAESRALSANSLAEAERARALAAHQERELAKQESALARRAEQEARNKERAAQEAAERERQERVAERQQAAEHYKELL
2) IYDGKRGAAGSGAANGSQSDGSSSSTPSPTASPSSVLPPVLPPIPLSPLPRNETVTVPHTPPATPAVAIPSAPVL
3) PGDYSHPWGSIPSPHSQPSSSPRSLYSEPGPSPQGGLQPPNLYAQS
300
171
247
487
245
292










Molecular Recognition Features






MoRF SequenceStartStop




1) EPEFQIYEER
2) YSGYII
348
293
357
298