<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13676

Description ATP-dependent DNA helicase
SequenceMDVPDSEEEEDQDQEPVAAGISKLEAEIAGINRELKTIEDSVGRMLERQAHLAKQKEKLEVKVLAAQKVLSYPVQGWAGKYSWDDDIADLRKNLFGLAAFRKHQRETINCVLSGSDCFVIMPSGGGKSLCYQLPTMVLQAGVTLVVSPLLSLIQDQVMGLSVMGIEAAMLTSQIDKEEETRVYKALEHGGQDLRFVYVTPEKVAKSKRFMSKLEKCDKAGRLALIAIDEAHCCSQWGHDFRPDYHHLGILKKQFPKVPMMALTATATQRVQDDVQEMLGIQGCPKFVSSVNRPNLYYEVREKLAGATAVVDDMVAFIQEHYPSQQDSGIVYCFSRKECEQVASELSQRGISAGYYHADMNPRQRHEVHQNWSCNYLQVVVATVAFGMGINKPDVRFVLHHSLSKSVETYYQESGRAGRDGLPSRCVLYYRPTDVTRQSCMVFAEASGLENLYAMVAYCQSRQKCRREAIFRHFGEPLQPCNGMCDNCGDAGTVRKLDITDKAEALVALLRALAGKEKRATLLQLCEQWKDKAVGKEDKERAVVQLLLDGVLAEEFGHTAFATNSYITRGPSLPLLEHGHLKVFLEVSDSSEKTCAGRGPDTSTSAAAGGDSVLESALDGLRRNVARQHGGIFPHSVLSTAQIALICKERPAHLAELRQLVGARIAGAYGDQILAVLRNPNQQPDALPPSNRSGPAKVAPESGAGPSAAPQSGRVEASRQRREDENFASEPSTSKIASKKGKEKVTRPSKVGPPHGKRKLADPSAVIDLDDSSGEAASGEGNRANQAAQGEPSSDDDFVLFHRKRRLQRTRT
Length811
PositionUnknown
OrganismKlebsormidium nitens (Green alga) (Ulothrix nitens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Klebsormidiophyceae> Klebsormidiales> Klebsormidiaceae> Klebsormidium.
Aromaticity0.06
Grand average of hydropathy-0.419
Instability index41.88
Isoelectric point7.07
Molecular weight89117.15
Publications
PubMed=24865297

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
DNA helicase activity	GO:0003678	IEA:UniProtKB-EC
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.21|      24|      69|     701|     726|       1
---------------------------------------------------------------------------
  703-  726 (42.93/32.24)	AGPSAA....PQSGRVEASRQRR..........EDENF
  760-  797 (27.28/10.98)	ADPSAVidldDSSGEAASGEGNRanqaaqgepsSDDDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.91|      23|     285|     212|     236|       5
---------------------------------------------------------------------------
  212-  236 (40.80/28.88)	KLEKCDKAGrlALIAIDEA...........HCCSQW
  495-  528 (33.11/17.51)	KLDITDKAE..ALVALLRAlagkekratllQLCEQW
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13676 with Med34 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QILAVLRNPNQQPDALPPSNRSGPAKVAPESGAGPSAAPQSGRVEASRQRREDENFASEPSTSKIASKKGKEKVTRPSKVGPPHGKRKLADPSAVIDLDDSSGEAASGEGNRANQAAQGEPSSDDDFVLFHRKRRLQRTRT
671
811

Molecular Recognition Features

MoRF SequenceStartStop
1) HGKRKLADPSAVIDLDDSSGEAA
2) RANQAAQGEPSSDDDFVLFHRKRRLQRTRT
754
782
776
811