<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13674
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MGTEVKRTERLAVALENALLEIHQLERTVMAYKESNQVLLFDRIDSFVKELKHVKKSAEGLDIEIPGEVVSLVDEGRNPDLYTREFLERCLDRNQATKGRVDAFKELRGHLLDNLDDAFPEEAQVYRDMKSAAADKLEKNSSHEQEERPLNGTENVAVKMEPPNDVELLQGSESVRSISVQVQPKSEPQI |
Length | 190 |
Position | Middle |
Organism | Klebsormidium nitens (Green alga) (Ulothrix nitens) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Klebsormidiophyceae>
Klebsormidiales> Klebsormidiaceae> Klebsormidium.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.663 |
Instability index | 36.66 |
Isoelectric point | 4.89 |
Molecular weight | 21569.99 |
Publications | PubMed=24865297
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13674
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 142.60| 44| 71| 15| 58| 1
---------------------------------------------------------------------------
15- 58 (72.03/48.02) LENALLEIHQLERTVMAYKESNQVLLFDRIDSFVKELKHVK..KSA
87- 132 (70.57/46.92) LERCLDRNQATKGRVDAFKELRGHLLDNLDDAFPEEAQVYRdmKSA
---------------------------------------------------------------------------
|