<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13664

Description Uncharacterized protein
SequenceRHCASSEQLICHWNHCRHRKCPVCFPIKNTNLASNILGQLRRKFGINPMPPNQAWNAGVNLDLRNHLIKKLIKAIYPVSFQNSIDSRVKSVSQYAAKLENMMFENASSREDYYQKLAEKIFYVRKGLDVDANNLKDKIGMEYLPFPPPLSVNHVLQELKSSILQSQMGGNFCNNCETSIKFRWHCKECKDYNLCSTCYHKIDHEHPMEKLFPISSGIVDKWLKEGSVELTVTRVNMHGPPGAGKTCAQHLLLNEGPPTECVTDSTPIARPAVRATRISADNLKWEKVTRTGLLERLASDLNVAVASQYEEHTGTTSPLQQHSDPSASIINSASIEINESIVSDNEASSISNEANNDETETVIQEILDKIQQSGVQLSGHWLYVIDSGGQPAYQELLPLFIRTASLNIITLDLSKPLDRKLDFQYRIGRETFSCGLNLKYSNREFFQSAVSSGAILKPIDVPHVLETPSHPMHFVLGTHYDLISQDSLKKIDEELMSSLKPDVQNYVVPNKRGESIVFPVNTLIPEDKERTAAGQKLCQSIANCGGTSLKMHMPIRWFAFELWLQKVAEKESRNVLIIDEVISAGTRFKMSENDTKDALQYLHNVTIVLYFPDILPELVFVDPQPILEILSRLLALTYVERSALHLITNPVPLDEDIDKLHNFGFFQEKLLDHLKSDVELFFPPHFVPSHLIGLLIHLRVITKGREGDYFFPCALRPYTNLSVSQTETKPLLIIWQDKHGHYGVNSLPVPQGMFPLLITHLLNQNDHSFSIEFPPLKPQYYKYRDALSLWIKIRRKRYTLHIINRYTHIEVYFVGSVEKAKENCPYIREVVMTAVNQSADAINVKRNHINAFHCPNKERNCYCVVEEDYLVNCTLCATSADISEDDESYWCWFHLKDCGLTDCTPEALIQVLQSPLAVELDISDLDQILTYMKEGHFPNECWFDLGLKLGLYHGTLKDIRLNFSKEGSHVCLRECLARWLERADGVDRKGGANWTTLVNCLEEYDKNSAERIRCKRLREAADQSLTDPELCPTSSNLRSNLVSGLNEQDDITPLQLVISIPLHSANTGVQLPTNGNIISSQNVVVGASGDSTPSIPLPQLPPVMSSGQPSSASNDPEKRKLIQQQLVLLLHAHRCQQREREQQVHGGFRPCALPHCRTMKNVLNHMTECQAGRDCQFPHCASSRQIIYHWKNCHQQECPVCLPLKNTTRPNVGSSIGGVPNSMFGGDVPPVSLPPHLVPTAAGAMAPGQNPPLPQKASQPQGGGGGVNPNPMGPAPGLPPSSTSGPMGPNQSMPPNHVRAWHAEVNLDLRNHLIKKLVEAIYPVPNPNSMHDSRVKSLFQYAVKVENMMFENASSREDYYQKLAEKIYRVRKELDEKRRMNERRKGAPNGFPDDGLHPITAVPQMQGQPNSHSQGAPGFPFNEFSNPSLSFPLTPFSETTQKDVLKELISSIPGGTGPPPSSNNNFEDQTPQSALRAHLLSPTRTNLPPSSATPPVSMADMEGIKIKTETLISKPESQAPLPISAPPSALPNMRTPQTPQETSVASKRMGPVGARPMMQPARFNMHQYRPGGMDPGPGIGMGLSSGLNYMYICNNCSTHVEFRWHCKECDDYDLCTTCYHKIGHEHPMERLGFNMEDKEPESFVSTTVSRVEMQKQRIKFLIHACQCSDSSCSKQLCIKMKQLLRHAQNCKMRSSGKCSVCNFFVKLCAAHAQECREIKCPVPLCANLKKKTRERRMREQSRSFQLADRQIMAMNRSHLFPLTTTNEESSNKSSAKQTGIVNKWLKEGSVELTVTRVNLHGPPGAGKTCALQLLLNEDPPTEHVTDSTPIARPTVRATRVSVDNLKWEKVTRAGLLERLASDLIAAAATQPEECIESTSPLNVPAHQPERHNDPIINSTSIGNSAPPIINSDPITNSDSDPIISPTSSIDSDSIETNETIISDNEGSSVSNEASNDETETVIQEILGAIQRSAVQLNDDWLYIIDSGGQPAYQELLPLFIRTASLNIITLDLSQPLDKKLDFQYRIGGETFLCGLNLKYSNREFFQSAVSSGAILKPIHVPHVLETPSHPMHFVLGTHYDLINQDSLKKIDEELMSSLKPDIQNYVVPNKRGESIIFPVNTLIPEDEGRLAAGQKLCQSIANCGGTSLKINMPIRWFAFELWLHKVAEKKSRNVLIIDEVISAGTRFQMSENDTKDALRYLHNVTIVLYFHDILPELVFVDPQPILEILSRLLALTYVERSALHLITNPVPLDEDINKLHNFGFFQKELLSHLKSDVKLFFPPHFEPSHLIKLLIHLRVITKATGGNYFFPCALQPYTDLPMPQTETKPLLIVWQETHDHFGLNSLPVPQGLFPLLITHLLNQKDHSCIIEFPPLKPRYYKYRDALSLWIKIKRKRYTLHIINRYTHIEVYFVGSIEKAKENCLYIREIVMTAVNQSADAINVKRNHINAFFCPKERNCYCVVEEDYLVNCTLCDTSADIHEDNESYWCWFGLTDCSLTECTHEAQTPGKSTSISVV
Length2516
PositionTail
OrganismAmphimedon queenslandica (Sponge)
KingdomMetazoa
LineageEukaryota> Metazoa> Porifera> Demospongiae> Heteroscleromorpha> Haplosclerida> Niphatidae> Amphimedon.
Aromaticity0.07
Grand average of hydropathy-0.359
Instability index51.63
Isoelectric point6.50
Molecular weight282745.87
Publications
PubMed=20686567

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP13664
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     174.87|      25|      26|     663|     687|       1
---------------------------------------------------------------------------
  663-  687 (52.63/30.46)	GFFQEKLLDHLK.....SDVELFFPPHFVP
  692-  716 (35.71/18.16)	G.....LLIHLRvitkgREGDYFFPCALRP
 2262- 2286 (51.91/29.94)	GFFQKELLSHLK.....SDVKLFFPPHFEP
 2291- 2315 (34.63/17.38)	K.....LLIHLRvitkaTGGNYFFPCALQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     158.01|      22|      25|     729|     750|       2
---------------------------------------------------------------------------
  729-  750 (46.09/23.21)	PLLI...IWQDKHGHYGVNSLPV.PQ
  754-  778 (33.84/15.07)	PLLIthlLNQNDHS.FSIEFPPLkPQ
 2328- 2349 (45.98/23.14)	PLLI...VWQETHDHFGLNSLPV.PQ
 2353- 2377 (32.10/13.92)	PLLIthlLNQKDHS.CIIEFPPLkPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     231.87|      48|     351|     499|     546|       3
---------------------------------------------------------------------------
  499-  546 (101.11/58.98)	KPDVQNYVVPNKRGESIVFPVNT...LIPEDKERTAAGQKLCQSIANCGGT
 1218- 1248 (29.12/11.61)	........VPNSMFGGDVPPVSLpphLVPTAAGAMAPGQ............
 2098- 2145 (101.64/59.33)	KPDIQNYVVPNKRGESIIFPVNT...LIPEDEGRLAAGQKLCQSIANCGGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     281.50|      41|     235|     381|     421|       4
---------------------------------------------------------------------------
  381-  421 (78.70/50.41)	LYVIDSGGQPAYQ...ELLPL.FIRTASLNIITLDLSKPLDRKLD
  617-  657 (62.41/38.21)	LVFVDP..QPILEilsRLLALtYVERSALHLITNPV..PLDEDID
 1980- 2020 (78.89/50.56)	LYIIDSGGQPAYQ...ELLPL.FIRTASLNIITLDLSQPLDKKLD
 2216- 2256 (61.50/37.53)	LVFVDP..QPILEilsRLLALtYVERSALHLITNPV..PLDEDIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|    1574.31|     478|    1597|     171|     914|       5
---------------------------------------------------------------------------
  215-  914 (858.61/700.97)	SGIVDKWLKEGSVELTVTRVNMHGPPGAGKTCAQHLLLNEGPPTECVTDSTPIARPAVRATRISADNLKWEKVTRTGLLERLASDLNVAVASQYEEHTGTTSPL.......QQHSDP...SASIINSA......SIEINESIVSDNEASSISNEANNDETETVIQEILDKIQQSGVQLSGHWlyvidsggqpayqellplfirtaslniitldlskpldrkldFQYRIGRETFSCGLNLKYSNREFFQSAVSSGAILKPIDVPHVLETPSHPMHFVLGTHYDLISQDSLKKIDEELMSSLkpdvqnyvvpnkrgesivfpvntlipedkertaagqklcqsiancggtSLKMHMPIRWFAFELWLQKVAEKESRNVLIIDEVISAGTRFKMSENDTKDALQYLHNVTIVLYFPDILPElvfvdpqpileILSrllaltyversalhlitnpvpldedidKLHNFgffqeklldhlksdvelffpphfvpSHLIgllihlrVITKGregdyffpcalrpYTNLSVSQTETKplliiwqdkhghygvnslpvpqGMFplliTHLlnqndhsfsiefpplkpqYYKYRDALSLWIKIRRKRYTLHIINRYTHIEVYFVGSVEKAKENCPYIREVVMTAVNQSADAINVKRNHINAFHCPnKERNCYCVVEEDYLVNCTLCATSADISEDDESYWCWFHLKDCGLTDCTPEAliqvlQSP
 1777- 1904 (75.45/27.37)	TGIVNKWLKEGSVELTVTRVNLHGPPGAGKTCALQLLLNEDPPTEHVTDSTPIARPTVRATRVSVDNLKWEKVTRAGLLERLASDLIAAAATQPEECIESTSPLnvpahqpERHNDPiinSTSIGNSA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 1907- 2507 (640.26/441.70)	....................................IINSDPITN..SDSDPIISPT.......................................................................ssidsdSIETNETIISDNEGSSVSNEASNDETETVIQEILGAIQRSAVQLNDDWlyiidsggqpayqellplfirtaslniitldlsqpldkkldFQYRIGGETFLCGLNLKYSNREFFQSAVSSGAILKPIHVPHVLETPSHPMHFVLGTHYDLINQDSLKKIDEELMSSLkpdiqnyvvpnkrgesiifpvntlipedegrlaagqklcqsiancggtSLKINMPIRWFAFELWLHKVAEKKSRNVLIIDEVISAGTRFQMSENDTKDALRYLHNVTIVLYFHDILPElvfvdpqpileILSrllaltyversalhlitnpvpldedinKLHNFgffqkellshlksdvklffpphfepSHLIkllihlrVITKAtggnyffpcalqpYTDLPMPQTETKpllivwqethdhfglnslpvpqGLFplliTHLlnqkdhsciiefpplkprYYKYRDALSLWIKIKRKRYTLHIINRYTHIEVYFVGSIEKAKENCLYIREIVMTAVNQSADAINVKRNHINAFFCP.KERNCYCVVEEDYLVNCTLCDTSADIHEDNESYWCWFGLTDCSLTECTHEA.....QTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     505.73|     136|    1243|      45|     181|       6
---------------------------------------------------------------------------
   45-  181 (257.69/180.60)	GIN.PMPPN..QAWNAGVNLDLRNHLIKKLIKAIYPVSFQNSI.DSRVKSVSQYAAKLENMMFENASSREDYYQKLAEKIFYVRKGLDvDANNLKDKIGMEYLPFPP....PLSVNHVLQELKSSILQSQMGGNFCNNCETSIKF
 1287- 1430 (248.03/169.38)	GPNqSMPPNhvRAWHAEVNLDLRNHLIKKLVEAIYPVPNPNSMhDSRVKSLFQYAVKVENMMFENASSREDYYQKLAEKIYRVRKELD.EKRRMNERRKGAPNGFPDdglhPITAVPQMQGQPNSHSQGAPGFPFNEFSNPSLSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     147.92|      21|      23|    1146|    1168|       7
---------------------------------------------------------------------------
    3-   27 (35.85/22.63)	CA.SSEQLIC..HWNHC......rhrkcP....VCFPI
 1155- 1178 (33.40/26.38)	CR.TMKNVLN..HMTEC...qaG....rD....CQFPH
 1179- 1203 (34.17/21.09)	CA.SSRQIIY..HWKNC......hqqecP....VCLPL
 1676- 1699 (23.98/11.78)	CI.KMKQLLR..HAQNCkmrssG.....K....CSV..
 1700- 1723 (20.53/ 8.63)	CNfFVK..LCaaHAQEC............reikCPVPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     116.05|      22|      24|    1530|    1552|       8
---------------------------------------------------------------------------
 1250- 1267 (26.08/ 9.83)	.....PPLPQKASQPQGG.....GGG.VN
 1270- 1285 (25.91/10.00)	P.M....GPAPGLPPSST.....SGP...
 1530- 1552 (36.38/21.58)	PNMRtPQTPQETSVASKR.....MGP.VG
 1555- 1579 (27.68/11.24)	PMMQ....PARFNMHQYRpggmdPGPgIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.25|      30|    1418|     182|     211|       9
---------------------------------------------------------------------------
  182-  211 (72.48/48.15)	RWHCKECKDYNLCSTCYHKIDHEHPMEKL.F
 1602- 1632 (68.77/45.25)	RWHCKECDDYDLCTTCYHKIGHEHPMERLgF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.08|      27|      28|    1435|    1461|      10
---------------------------------------------------------------------------
 1435- 1461 (48.30/24.92)	FSETTQKDV.LK.ELISSIPGGTGP.....PPSS
 1465- 1490 (39.19/18.77)	FEDQTPQSA.LRaHLLS..PTRTNL.....PPSS
 1495- 1527 (23.59/ 8.22)	VSMADMEGIkIKtETLISKPESQAPlpisaPPS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.61|      22|      23|    1068|    1089|      11
---------------------------------------------------------------------------
 1031- 1049 (18.83/ 7.28)	...PTSSNLRS..NLVSGlnEQDD
 1068- 1089 (37.77/23.74)	VQLPTNGNIISSQNVVVG..ASGD
 1094- 1114 (37.00/23.07)	IPLPQLPPVMSSGQ.PSS..ASND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.94|      26|      31|     915|     940|      12
---------------------------------------------------------------------------
  915-  940 (47.98/30.60)	LAVELDI..SDLDQI.LTYMKEG.HF.PNEC
  944-  974 (27.95/14.56)	LGLKLGLyhGTLKDIrLNFSKEGsHVcLREC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.43|      14|      15|    1743|    1756|      13
---------------------------------------------------------------------------
 1743- 1756 (24.10/23.85)	FQLADRQIMAMNRS
 1759- 1772 (23.33/22.72)	FPLTTTNEESSNKS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13664 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAATQPEECIESTSPLNVPAHQPERHNDPIINSTSIGNSAPPIINSDPITNSDSDPIISPTSSID
2) KDVLKELISSIPGGTGPPPSSNNNFEDQTPQSALRAHLLSPTRTNLPPSSATPPVSMADMEGIKIKTETLISKPESQAPLPISAPPSALPNMRTPQTPQETSVASKRMGPVGARPMMQPARFNMHQYRPGGMDPGP
3) RPNVGSSIGGVPNSMFGGDVPPVSLPPHLVPTAAGAMAPGQNPPLPQKASQPQGGGGGVNPNPMGPAPGLPPSSTSGPMGPNQSMPPNHVRAWHAEV
4) SGDSTPSIPLPQLPPVMSSGQPSSASNDPEK
5) TCALQLLLNEDPPTEHVTDSTPIARPTVRAT
6) VRKELDEKRRMNERRKGAPNGFPDDGLHPITAVPQMQGQPNSHSQGAPGFPFNEF
1865
1441
1208
1087
1807
1369
1929
1576
1304
1117
1837
1423










Molecular Recognition Features






MoRF SequenceStartStop




NANANA