<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13638

Description Uncharacterized protein
SequenceMPGTAQGIKEELLRAIDESGNVLDMKLLVSVLNDLESVRITAEDLTVTRLGLYINNARRQTKDKTLARRMKDLLKEWKILVQNSQSNGVAPPSQLTTPSISPAPLSTTPALALSEEPSSESGLVTPKQNPQLSHRKLLLSKLSAFKKPQTTPTATPPTIEPINTSHSLPLAPPPPLHVSNGKPGSTNNSLTIRYPLDRLPKQQETRGPLIVSISLSLIKLSGRNEAPPTEGVPLLHPGLNERSSPLSFQSLSPVSYQETRPSPLPPPSLSLPLPPPPSLSLPPSPSSLTPPLIVSIPLSLLTSPTLVPAARNRSRXXXXRLGNRSRRQCNRYMKKKPVPLGTSLTVYLVKLYVA
Length354
PositionUnknown
OrganismAmphimedon queenslandica (Sponge)
KingdomMetazoa
LineageEukaryota> Metazoa> Porifera> Demospongiae> Heteroscleromorpha> Haplosclerida> Niphatidae> Amphimedon.
Aromaticity0.03
Grand average of hydropathy-0.336
Instability index64.60
Isoelectric point10.30
Molecular weight37904.50
Publications
PubMed=20686567

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13638
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     167.99|      39|     101|     161|     199|       2
---------------------------------------------------------------------------
   96-  142 (43.89/ 9.67)	TTPSISPAPLSTTPALALSE.EPSSESGLVT...PkqnpqlshrkllLSKL
  161-  199 (73.25/20.12)	PINTSHSLPLAPPPPLHVSNGKPGSTNNSLTIRYP............LDRL
  270-  301 (50.84/12.14)	......SLPLPPPPSLSLPPS.PSSLTPPLIVSIP............LSLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.78|      14|      73|     256|     269|       3
---------------------------------------------------------------------------
  223-  239 (21.28/ 6.01)	RNEAPPTegvPLLHPGL
  256-  269 (29.50/11.05)	YQETRPS...PLPPPSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13638 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QSNGVAPPSQLTTPSISPAPLSTTPALALSEEPSSESGLVTPKQNPQLS
2) RKLLLSKLSAFKKPQTTPTATPPTIEPINTSHSLPLAPPPPLHVSNGKPGSTNNSLTIRYPLDRLPK
3) SGRNEAPPTEGVPLLHPGLNERSSPLSFQSLSPVSYQETRPSPLPPPSLSLPLPPPPSLSLPPSPS
85
135
221
133
201
286










Molecular Recognition Features






MoRF SequenceStartStop




1) VSVESLHTTRVKEINYDGEEIYEGRPSLSQKLSELAQHVDFREERADDDNDREEGKKKQEEEEEEGVSGPTTKKPSHRWPWEFAHKTQDSKQYSDMIMASLIDDSNNDLSEELAKGETVLLDLSDEYDDPDQDFEA
15
150