<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13623

Description Uncharacterized protein
SequenceMAGNLRSDLVAGLNEQDDITPLQLVISIPLHSANTGVQLPTNGNIISSQNVVVGASGDFTPSLPSRQPPIMGGGQPSSASNDPEKTKLIQQQLVLLLHAHRCQQIEREKGTLWKPCQLPHCRTMKNVLNHMTDCQAGRDCQFPHCASSRQIIYHWKNCNQQECPVCLPLKNTTRPNVGGSIGGVPNSMFGGDVPPVSLPPHLVPKATGAMAPGQNPPLPQKAGQPQGGGVGGVNPNPMGPAPGLPPSSTSGPMGPNQSIPPNQSAMPPNHVKAWHAEVNLDLRNHLIKKLVEAIYPVPNPNSMHDSSVKSLFQYAVKVENMMFENASSREDYYQKIAEKIYRVRKELDEKRQMHERRKGFVPFSSPPVSVNNVLQELKSSIPLSAMGGTYCNNCSTNIKFRWHCKECWYYNLCSTCYPVVGHVHPMEKLFPVSN
Length434
PositionTail
OrganismAmphimedon queenslandica (Sponge)
KingdomMetazoa
LineageEukaryota> Metazoa> Porifera> Demospongiae> Heteroscleromorpha> Haplosclerida> Niphatidae> Amphimedon.
Aromaticity0.06
Grand average of hydropathy-0.464
Instability index56.73
Isoelectric point8.90
Molecular weight47493.90
Publications
PubMed=20686567

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13623
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     179.04|      42|      43|     175|     217|       1
---------------------------------------------------------------------------
  175-  217 (81.08/41.89)	PNvGGSIGGV.PNSMFGGDVPP......VSLPPHLVPKATGAMAPGQNPP
  225-  260 (66.66/30.40)	PQ.GGGVGGVnPNPM.G.PAP........GLPP...SSTSGPMGPNQSIP
  265-  300 (31.30/10.20)	.............AMPPNHVKAwhaevnLDLRNHLIKKLVEAIYPVPNP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.19|      22|      22|     114|     135|       2
---------------------------------------------------------------------------
   96-  127 (36.86/20.23)	LLHAHRCQqierekgtlwKPCQ...LPHCRTMKNV
  128-  151 (38.99/21.82)	LNHMTDCQ........agRDCQ...FPHCASSRQI
  152-  171 (25.35/11.64)	IYHWKNCN..............qqeCPVCLPLKN.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.20|      19|      39|       3|      21|       3
---------------------------------------------------------------------------
    3-   21 (32.51/21.17)	GNLRSDLVAGLNEQDDITP
   43-   61 (32.69/21.31)	GNIISSQNVVVGASGDFTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.11|      25|      49|     303|     328|       4
---------------------------------------------------------------------------
  303-  328 (39.79/34.16)	MHDSSvKSLFQYA...VKVENMMFENASS
  353-  380 (38.32/27.54)	MHERR.KGFVPFSsppVSVNNVLQELKSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13623 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RPNVGGSIGGVPNSMFGGDVPPVSLPPHLVPKATGAMAPGQNPPLPQKAGQPQGGGVGGVNPNPMGPAPGLPPSSTSGPMGPNQSIPPNQSAMPPNHVKAWH
174
275










Molecular Recognition Features






MoRF SequenceStartStop




NANANA