<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13594
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MLSRFQASYQRVEVSLQKLTDSIAAYNPSITAADELVAADEAVNANIDQLVKHQKNHQRILSLRQTSEALDESLKSTLRLLAETRKEIQAIPSASSSSRREVTVDELLDYAKFIARTTVPPTFRRPIPDDLLPKKQAAPAVQPSNGMVTPPPASAGPLIDSLATVADDSNPNYNQTTSPAEENLAVKAMEDREKAFIIPQNLPFEPWPNHTIIMRGSLADIQRLAESGVDPASILSREEKAEAERLRKEREEEEAREAEVRERKRREDWSDQAARRPTVADNKPFNPDDL |
Length | 290 |
Position | Middle |
Organism | Zymoseptoria tritici ST99CH_3D7 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Zymoseptoria.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.688 |
Instability index | 52.34 |
Isoelectric point | 5.13 |
Molecular weight | 32395.85 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13594
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.30| 16| 19| 245| 262| 1
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245- 260 (24.33/13.70) RLRKEREEEEAREAEV
264- 279 (27.97/10.39) KRREDWSDQAARRPTV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.09| 15| 19| 121| 139| 2
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121- 139 (23.06/19.55) PTFRRPIPddllPKKQAAP
143- 157 (27.04/13.08) PSNGMVTP....PPASAGP
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