Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MSGSYKVLQNEDLSRIQEILIPPKSENETFTIPPGSSSSKSSSTQSTVATTEFIPHIFYTLYQIQKDPNRSNNQLETKTGLIRHRLRNCKTLIRESDSSLELLSKSTNEWEQFITNRENELQIKKNVLLDLRSKISEILTNCNYEPDSEETDPVTEGKEEQQGELQQENKVEESEQGVKEEGEQSVKEENVQDNNEEEKSVNLKKNETEKINSPEQINEHQETVVETDNKSDKNNNNDDNSNPETATAELPNDDNEIQSTSVADDDNAILDDIEMEM |
Length | 277 |
Position | Middle |
Organism | Kazachstania saulgeensis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania. |
Aromaticity | 0.03 |
Grand average of hydropathy | -1.196 |
Instability index | 62.78 |
Isoelectric point | 4.35 |
Molecular weight | 31583.72 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP13579 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 57.59| 20| 20| 157| 176| 2 --------------------------------------------------------------------------- 147- 169 (29.07/12.39) DSEETDpvtEG.KEEQQGELQQEN 170- 190 (28.53/12.04) KVEESE...QGvKEEGEQSVKEEN --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 54.77| 17| 20| 206| 223| 4 --------------------------------------------------------------------------- 206- 223 (25.26/13.56) NETEKINSPEQiNEHQET 229- 245 (29.51/12.42) NKSDKNNNNDD.NSNPET --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AELPNDDNEIQSTSVA 2) ATTEFIPHIFYTLYQI 3) NAILDDIEMEM 4) TFTIPP 5) VLQNEDLSRIQEILI | 248 49 267 29 7 | 263 64 277 34 21 |
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