<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13572

Description Similar to Saccharomyces cerevisiae YGL025C PGD1 Subunit of the RNA polymerase II mediator complex
SequenceMTNVGAGNETESGTAVESILTLHMKLEELERRLAQNPQGKEQLALTLSTTRESILPIRLELNNFIHMVSNIADDKNGITNQEKFHNVRTMLLKLHTSIQSLSQRFQELSPLFGTVPEYTTEYKSKEYQPLETLTPTNIPQTPAVNDPSNKATSGNTATSNTTATNTNNITSTGAPATTTTTTATKKGRGSAASLKSPPTAANTPTTGTATPATTSTNASTTTAKKPRKPRQKKSVSSAKNTPAATHATTTNTNSVVATPLSATTMNPTLSVPPQLMTGMIPGNIVGMSPTNTMMNMAPQMQPQMQFNSNNMNNRQTGNTPGPQGQLSPQNNTITPANILSMGSNNNITNNSNLVSNNSNNNNNNNNNQGPNAMNDFGNLDLNNIDLSSLNMDFL
Length394
PositionTail
OrganismKazachstania saulgeensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.03
Grand average of hydropathy-0.684
Instability index32.24
Isoelectric point9.40
Molecular weight42045.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13572
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.54|      29|      34|     150|     180|       1
---------------------------------------------------------------------------
  150-  180 (40.77/16.20)	KAtSGNTAT..SNTTATNTNNiTSTGAPATTTT
  186-  216 (39.77/10.44)	KG.RGSAASlkSPPTAANTPT.TGTATPATTST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.53|      24|      32|     255|     286|       2
---------------------------------------------------------------------------
  258-  282 (40.95/19.35)	TPlSATTMNPTLSVPPQL..........MTGMIPG
  288-  321 (40.58/13.37)	SP.TNTMMNMAPQMQPQMqfnsnnmnnrQTGNTPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.95|      16|      34|      14|      29|       3
---------------------------------------------------------------------------
   14-   29 (25.77/16.92)	TAVESILTLHMKLEEL
   49-   64 (27.18/18.18)	TTRESILPIRLELNNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.99|      24|      32|     329|     357|       4
---------------------------------------------------------------------------
  329-  357 (33.64/23.05)	QNNTITPANILSMGsN...NNItnnsNLVSNN
  364-  390 (40.35/16.09)	NNNNQGPNAMNDFG.NldlNNI....DLSSLN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13572 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) VPEYTTEYKSKEYQPLETLTPTNIPQTPAVNDPSNKATSGNTATSNTTATNTNNITSTGAPATTTTTTATKKGRGSAASLKSPPTAANTPTTGTATPATTSTNASTTTAKKPRKPRQKKSVSSAKNTPAATHATTTNTNSVVATPLSATTMNPTLSVPPQLMTGMIPGNIVGMSPTNTMMNMAPQMQPQMQFNSNNMNNRQTGNTPGPQGQLSPQNNTITPANILSMGSNNNITNNSNLVSNNSNNNNNNNNNQGPNAMNDFGNLDLN
115
382










Molecular Recognition Features






MoRF SequenceStartStop




NANANA