<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13569

Description Similar to Saccharomyces cerevisiae YDL005C MED2 Subunit of the RNA polymerase II mediator complex
SequenceMVAKNSVTIENVNSPTTQLHKNKLTQCFDDMMRMSSEMLVQEQLKTIQLDNGITNGFSATHQKNLKEKFHVFHGILDDLDITLDKCATYVETLNKIGIEKEELRKKEEELEAERQKKLEEEKEQQRIAKEELMKKEKEEQEQKEKEKQEKEKREKEKREAQQKENNVTGNALDLMDDMRLSFNDDVGVNVDGTQNDLLGSFNSGDKGSNNTPGILAASAGVNDISDPLQSLTSAGETDDKNNSSNKSNNNKGSNNNANNANDTGANSVFNDLDAMDMSLFTDLDNTNFDPLSETLNGTNDLTGKDTAMNDNNNNSNNNDTNNNNSNNNNGSTNNNQISTDNGATATTGAINVDNENNGNVMVNNNNDSLNMMEPLQDMGDDYLTLNDFNDLNIDWNAGGDSGDLDLNDFNI
Length411
PositionTail
OrganismKazachstania saulgeensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.03
Grand average of hydropathy-1.120
Instability index26.90
Isoelectric point4.32
Molecular weight45617.67
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13569
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     227.29|      42|      42|     284|     325|       1
---------------------------------------------------------------------------
  184-  218 (38.31/ 9.04)	........DDVGVNVDGTqNDLLG...SFN.S.GDKGSNNTPGILAAS
  222-  262 (56.48/16.73)	ND...IS.DPL.QSLTSA.GETDDKNNSSN.KsNNNKGSNNNANNAND
  284-  325 (79.40/26.43)	DN...TNFDPLSETLNGT.NDLTGKDTAMN.D.NNNNSNNNDTNNNNS
  327-  368 (53.09/15.30)	NNngsTNNNQIS.TDNGA.TATTG...AINvD.NENNGNVMVNNNNDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.93|      15|      20|     119|     138|       2
---------------------------------------------------------------------------
  119-  138 (16.02/21.62)	EEEKEQQRiaKEelmKKEKE
  142-  156 (24.91/13.51)	QKEKEKQE..KE...KREKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.68|      11|      20|     377|     389|       3
---------------------------------------------------------------------------
  377-  389 (18.67/12.94)	DMGDdyLTLNDFN
  400-  410 (23.01/ 9.56)	DSGD..LDLNDFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.99|      17|      26|      49|      65|       4
---------------------------------------------------------------------------
   49-   65 (30.46/18.35)	LDN.GITNGFSATHQKNL
   76-   93 (25.53/14.29)	LDDlDITLDKCATYVETL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.97|      11|      97|     170|     182|       5
---------------------------------------------------------------------------
  170-  182 (13.47/15.68)	NALDLMdDMRLsF
  270-  280 (22.50/12.72)	NDLDAM.DMSL.F
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13569 with Med2 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KEELRKKEEELEAERQKKLEEEKEQQRIAKEELMKKEKEEQEQKEKEKQEKEKREKEKREAQQKENNVTGNALDLMDDMRLSFNDDVGVNVDGTQNDLLGSFNSGDKGSNNTPGILAASAGVNDISDPLQSLTSAGETDDKNNSSNKSNNNKGSNNNANNANDTGANSVFNDLDAMD
2) SLFTDLDNTNFDPLSETLNGTNDLTGKDTAMNDNNNNSNNNDTNNNNSNNNNGSTNNNQISTDNGATATTGAINVDNENNGNVMVNNNNDSLNMMEPLQDMGDDYLT
100
278
276
384










Molecular Recognition Features






MoRF SequenceStartStop




1) DLDLNDFNI
2) MMEPLQDMGDDYLTLNDFNDLNIDWNAG
403
371
411
398