<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13558
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MDLTDLHPPDDYSHRFFIWHEWIQAHGPLTNENVFDYFATSMFYDKQSNNQVLRMQTMHTGVPLENEAEELRRFTGIEFAVVHAQPPSLFIIHKRERLSPDEVRPLAAYFIMNNRIYQSPDVYTLISNRLLTSLHALQSSMTTLRTHRPAYTPRTGFAWPIVEPAAPDDASKARDGADEPPESNATETASTTEDQALAEPSAKRKLPAHERQQNNLLLFNAMRTTAVHASKSFTLPAAAAEDIVPDTPGLRSQPRSSATPAPAPTRAATPKMGPTPQEQPPVKGPPGGGKKKKKRIATMMNVTS |
Length | 304 |
Position | Head |
Organism | Postia placenta MAD-698-R-SB12 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Polyporales> Dacryobolaceae> Postia.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.616 |
Instability index | 57.08 |
Isoelectric point | 7.21 |
Molecular weight | 33841.79 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13558
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 49.53| 13| 17| 248| 264| 1
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252- 264 (23.90/14.40) SQPRSSATPAPAP
268- 280 (25.63/ 6.67) ATPKMGPTPQEQP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 55.40| 16| 17| 166| 181| 2
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166- 181 (29.06/19.00) APDDASKARDGADEPP
185- 200 (26.34/16.54) ATETASTTEDQALAEP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 46.90| 12| 17| 90| 101| 3
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90- 101 (22.80/16.41) FIIHKRERLSPD
110- 121 (24.09/17.72) FIMNNRIYQSPD
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