<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13531

Description Fungal-specific transcription factor domain-domain-containing protein
SequenceMDPGFLPHQQQQQQQHQRHSSDEEHSDYYTLKTGKKRERATQACSPCRKKKKRCDGAKPNCKNCMEAGLECSYAVCKRRGPRKGYVQLLEERLAMLERRLSSLPVSPTSTSPTTTTVAATDDTGKKPTLLMESSSSESLDDIKMPKEDVVLHLVDFFFKYINSIFPLVHHSTLVQSIKDGSISPPLLWSVMAIGARFSDHPDIKTDPPYWAGEKFARKAGSMINNDLFEPTVPNLQFWGVMACLEYGRAAGSRAWIYGGLAARICFELGFHKEETLKLPVYKKDGTMDRVAMLMRRRIFWSCFNIDKYGSAGNSRPQFFSKGDYDVDLPDDESLALLNPLHQNVTVDYKPVKVDSLGSFIKYYLSLMELFGDVIKGLQRAKNNQNKAMWPPTDDFDQLNNELQAWKRDLPTHMDFSLEDLEYHLERASRGKINHYLCAHVIWRTLVLALHRGSLAYVDPPTNSNSNNNRRFASTFSPQMWDRIQYSVSMCKQVVNDVMPIFEAMKNICGVNVIPYMGYSSYMFATILMTSTFTNTEEEHRKGTKGLLLLYDMIELLRPYWPVCERLSVTTRDLIVSHSRMYEYSQEEHYKRTGYELPSSPRLRPFQSYPPSASASTESPSSTTTATTAPASTLSHQQNIPVSMINLLNSNDSPRQDVPLGYPSYSLSTIPASQQQQSSTLPQTSFSSSISAPSSLSSSALLSDTMDVGGSTFGDSGGGITDPYTSSGAIDFNSSAFLYDTGLFGQLMFDETKFMNDPSFFGLQQQQQQQQQQQQQQRPQQPMTFTQNNNSRILPSSSPTTTSPTTYMSSSTSPPILDYGKRTWEPVWRS
Length829
PositionTail
OrganismAbsidia repens
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Cunninghamellaceae> Absidia.
Aromaticity0.10
Grand average of hydropathy-0.539
Instability index58.78
Isoelectric point7.26
Molecular weight93540.50
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13531
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.09|      43|     753|       2|      46|       1
---------------------------------------------------------------------------
    2-   46 (72.20/46.27)	DPGFLPHQQQQQQQHQRHSSDEEHSDyYTLkTGKKRERATQACSP
  756-  798 (80.89/43.60)	DPSFFGLQQQQQQQQQQQQQQRPQQP.MTF.TQNNNSRILPSSSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.53|      27|     140|     472|     526|       2
---------------------------------------------------------------------------
  498-  526 (48.44/70.81)	MPIfeAMKNICGVNVIPY....MGYSSYMFATI
  639-  669 (44.09/14.09)	IPV..SMINLLNSNDSPRqdvpLGYPSYSLSTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.55|      57|     506|     171|     228|       4
---------------------------------------------------------------------------
  171-  228 (102.29/64.39)	STLVQSIKDGSISPP.......LLWSVMAI.GARFSDHPDIKTDPPYWAGE.KFARKAgSMINNDLF
  678-  743 (87.27/50.14)	STLPQTSFSSSISAPsslsssaLLSDTMDVgGSTFGDSGGGITDPYTSSGAiDFNSSA.FLYDTGLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.89|      20|     173|     234|     272|       8
---------------------------------------------------------------------------
  234-  253 (38.57/57.34)	NLQFWGVMACLEYGRAAGSR
  296-  315 (39.31/15.52)	RRIFWSCFNIDKYGSAGNSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.18|      23|      47|     536|     561|       9
---------------------------------------------------------------------------
  536-  561 (35.68/30.23)	EEEHRKGTkGLLLlyDMIELLRPY..WP
  585-  609 (41.50/23.52)	QEEHYKRT.GYEL..PSSPRLRPFqsYP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13531 with Med15 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) FQSYPPSASASTESPSSTTTATTAPASTLS
2) LSSLPVSPTSTSPTTTTVAATDDTGKKPTLLME
3) MDPGFLPHQQQQQQQHQRHSSDEEHSDYYTLKTGK
4) PSFFGLQQQQQQQQQQQQQQRPQQPMTFTQNNNSRILPSSSPTTTSPTTYMSSSTSPP
605
100
1
757
634
132
35
814

Molecular Recognition Features

MoRF SequenceStartStop
1) RKKKKR
2) SDYYTLKT
3) TSPPILDYGKRTWEPVWRS
48
26
811
53
33
829