<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13515

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMDLQRNAHVGLDPNTIQELETLRGKLWSLQETFAAQIAYLKEPKYPFTWPDLLNKFNMLTAKFASLSDDFYGYIETGSNATLPKLMLHPFIPTTTEQETNISSVLLRTKLIPDIERLELETQAAVARELSSHTTDHHHHHHHHHNNNNINNNNDTNNNNNGAEDDEQLIRSHYEQWTSHKQRHDRIAVDAANFVADLVNDYREDFLLRIEDQEAQEKEENEDEEDRDRAEDKAKPEEQEEGDEAWEKMGFPNKETWRRWKLECLVNLYSSGKDEVPGSDLKKMATRPAY
Length289
PositionHead
OrganismSyncephalastrum racemosum (Filamentous fungus)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Syncephalastraceae> Syncephalastrum.
Aromaticity0.08
Grand average of hydropathy-1.044
Instability index51.74
Isoelectric point4.96
Molecular weight33717.59
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13515
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.69|      16|      18|     208|     223|       1
---------------------------------------------------------------------------
  208-  223 (27.10/16.87)	RIEDQEAQEKEENEDE
  228-  243 (27.60/17.32)	RAEDKAKPEEQEEGDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.76|      17|      18|      76|      92|       2
---------------------------------------------------------------------------
   76-   92 (30.37/25.88)	TGSNATLPKLMLHP.FIP
   95-  112 (22.39/17.13)	TEQETNISSVLLRTkLIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.24|      20|     204|      48|      69|       3
---------------------------------------------------------------------------
   13-   32 (34.08/15.58)	PNTIQELETLRGKLWSLQET
   50-   69 (33.16/14.74)	PDLLNKFNMLTAKFASLSDD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13515 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FLLRIEDQEAQEKEENEDEEDRDRAEDKAKPEEQEEGDEAWEKM
2) QAAVARELSSHTTDHHHHHHHHHNNNNINNNNDTNNNNNGAEDDEQLIRSHYEQW
205
122
248
176










Molecular Recognition Features






MoRF SequenceStartStop




1) DEAWEKMGFPNKETWRRWKLECLVNLYSSGKDEVPGSDLKKMATRPAY
242
289