Description | "Mediator complex, subunit Med21" |
Sequence | MADRLTQLQDCFDQLATQFYASLRYISTHHPPSTSNNQPAAPAAPDPNPQDPNPPRPDSPSTFAAAQRELAHDLVLKEQQIEYLISVLPGIGTSEKEQEERIRVLERELREVEEERKQAVREKEESLERLDEVIRGVRRL |
Length | 140 |
Position | Middle |
Organism | Umbilicaria pustulata |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Lecanoromycetes> OSLEUM clade> Umbilicariomycetidae> Umbilicariales> Umbilicariaceae> Lasallia. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.893 |
Instability index | 62.83 |
Isoelectric point | 4.95 |
Molecular weight | 16038.66 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669 ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP13505 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) ERIRVL 2) FYASLRYI 3) IEYLISVLPGIG 4) TFAAAQRELAHDLVL | 100 19 81 62 | 105 26 92 76 |
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