<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13496

Description "Mediator complex, subunit Med15, fungi"
SequenceMNTGNFQNMAAMRGPTAGAQQQADLQRGGSQRQVQHILRTLAQQQHPPGWQTTVTAQQRTQYVWQLVSSLRLIKQDMDINDVIPIAISYESRMFRECSDKASYEQQCRDKLGQIRDTRSRQTANLQQQMQTPQPPQMGMMPQQMPVQGPMSNQNQSQFPSGFPNPQLQHPMQASPVPHQQQQSQAPQQLSMSYGIPNAQMPMQQVQQMSKNMYQPVGHMSQADISLTPEEKEQINRRAQKMAQNTPKAALDKIRNNLQNMTPEQRQHLMNQNMDPLAYFFHDAATRQFITAKASIQAQGHLRQGGLPPAGRLMLQQTRPISQNSLTMQGQPSAAVAVSQGFDPSFLGNMNQILGQQQDALRSQEAGHLVVPASDSQKLAQAQQQRGNYHGTPQPKMDGQAAIPRPIQNPRTMNQPQQQFFDAQQLQQENAQHVAQFQAQAQAQAQAQARMNAQSHAQQLQGQVGGLGNHLGARPAQQPSPAMPMLNRPLNQQSQQQGTPQQRPQQQTPNMNQMKSQEQTMVQQPPQQAPQQNIPPAAQRNRPMPAIQQQLENLPEDQRSVLLAQWQHRRQQQQQQHHRAQAMQLNGMQAIPSNAGPTQTQQSQPGQLPPQTLPPSHAKTSQAAPASNVNALQGPPSAQRLPQGTNVHQQFGQQQRDQAQHQEMVRRLNQQQRRAAELAATSLTEDQAREMDKVNFPTSILNANNALSQPPANVSTWGQLKSWVAQNAHTLPAESLGPLRGLQGLHYQSITNHQQRNMAQQMSQGQPGTQQTIPVNTALQAQSVTSRNTQPLMQTANIPQMVAPSGTTSLPPPTTQEIQATRARLPENMRTATDDFVRAIILRRRQTEMLRPGQGQQVMTQQQAQVMAMQRAQQQQPQQQQLQRQITQTPSTPLAPPPQVQPPQQGPISKVPVGQSNEKPPRPAQQGRQGPQAQAQGQATQKGVKRPNDDVVEVPNPNLTQKRQSQPQEQQQQQHSQAPTNAQNPNQQRFNVPQITAQQMVSMSPQQRHQIEETKKQAAERALAASQTQPISGIKAEGQAINEPQRNEENIRRDVRLKQIYHEVLQSTPKRPPLPLNPQIMGKMAQQLREAKGMVTKMEQSLPSFFRMFGDEDMTRELIRTRLLLVQQYRDKDYNPADHFNISPEELEASIAKLREYFALAMQKVLQQKHLQAQGIQQSVQDRQSQPPQVSQGRTPELNAANLQQQQQALQAAAQLKLQRNESHRHNRAPAAPTSTQPPFLLGAQSPDGTPHAYGPTVLTQDQLKFPPPKKRKPNQHGSAASTPAQVQATPASSSPPQMAKIPSPEAQRQQAVPQIFKYPVGGCDANKNGFSSQAELAKHTADIHEPKEPLIEDPLAWALESFRLGLGLDAHGKMKPRKEEAKAENKALEAPKMKLSASQQSQTPMKQEVGTPAGQTALPMSRAPTQTGPSPASQMLKTPQASITVKTPASAASGVKLETAKESKMKFPGGAAAVKEPPSPPPTDLWADSSISPAGISYCFSGLSDLQSVPWTELQTALTPPWSTPSGGRGGSSAKSDKNSPRASDIGENDNLNISIAAERAWMPNEWFEDGAGGLEGGGGYGGADLMDVDWESAFGKMVVREDAGREQGKEGKKKRGEWAAGPAAGFGPTGFSVML
Length1636
PositionTail
OrganismUmbilicaria pustulata
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Lecanoromycetes> OSLEUM clade> Umbilicariomycetidae> Umbilicariales> Umbilicariaceae> Lasallia.
Aromaticity0.04
Grand average of hydropathy-0.921
Instability index67.31
Isoelectric point9.87
Molecular weight180399.33
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13496
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     754.08|      78|      78|     468|     545|       1
---------------------------------------------------------------------------
  164-  235 (52.95/ 6.64)	N.........................PQLQHPMQAS..P...VPH..QQQQSQA..PQQ....L........smsygiPNAQ.....MP.MQQVQ.Q......M....S..KNM.Y.Q.PVG.HMSQA..DIsltP...eEK.EQI.N......
  316-  380 (58.57/ 8.29)	...QT............RPIS....QNS..LTMQGQ..P...SAA..VAVSQGF..D.....................P.SF.....LGNMNQIL.G......Q....Q..QDALR.S...Q.EAGHL..VV...P.......ASD.SQKLA.Q
  387-  465 (67.61/10.95)	NYHGTpqpkmdgqaaipRPIQ....NP........R..T...MNQ..PQQQFFD..AQQ....L..............QQEN.....AQHVAQFQ.A......Q....A..QA....Q.AQA.QARMN..AQ...S....HA.QQL.QGQVG.G
  468-  545 (150.51/35.27)	NHLGA............RPAQ....QPSPAMPMLNR..P...LNQ..QSQQQGT..PQQ....R..............PQQQ.....TPNMNQMK.S......Q....E..QTMVQ.Q.PPQ.QAPQQ..NI...P....PA.AQR.NRPMP.A
  548-  625 (64.67/10.08)	QQLEN............LPED....QRSVL............LAQ.wQHRRQQQ..QQQ....H..............HRAQ.....AMQLNGMQ.AipsnagP....T..QT..Q.QsQPG.QLPPQ..TL...P....PShAKT.SQAAP.A
  629-  692 (52.68/ 6.57)	NALQG............PPSA....QRLP......................QGTnvHQQ....F..............GQQQ.....R...DQAQ.H......Q....EmvRRLNQ.Q.QRR.AAELA..AT...S....LT.EDQ.AREMD.K
  751-  827 (67.10/10.79)	NHQQR............NMAQ....QMSQGQPGTQQtiP...VNTalQAQSVTS..RNT....Q..............PLMQ.....TANIPQMV.A......P....S..GTTSL.P.PP....TTQ..EI...Q.......ATR.AR.LPeN
  837-  917 (62.24/ 9.37)	RAIIL............RRRQtemlRPGQGQQVMT............QQQAQVM..AMQ....R..............AQQQ.....QPQQQQLQ.R......QitqtP..STPLA.P.PPQvQPPQQ..G....PiskvPV.GQS.NE.....
  918-  992 (60.16/ 8.76)	..KPP............RPAQ....QGRQG........P........QAQAQGQ..ATQkgvkR..............PNDDvvevpNPNLTQKRqS......Q....P..QEQQQ.Q.QHS.QAPTN..AQ...N....PN.QQRfNVP....
 1168- 1221 (60.06/ 8.73)	KHLQA............QGIQ....Q.....SVQDR...........QSQ......PPQ....V..............SQGR.....TPELNAAN.L......Q....Q..Q...Q.Q.ALQ.AAAQL..KL............QR.NE.....
 1222- 1314 (57.51/ 7.98)	...SH............R..H....NRAPAAPTSTQ..PpflLGA..QS.PDGT..PHA....YgptvltqdqlkfppPKKR.....KPNQHGSA.A......S....T..PAQVQaT.PAS.SSPPQmaKI...P...sPE.AQR.QQAVP.Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     129.84|      25|      26|    1399|    1423|       2
---------------------------------------------------------------------------
 1399- 1423 (45.18/22.44)	QQSQTPMK...........QEVGTPAGQTAL..PMSRA
 1426- 1452 (34.47/14.97)	QTGPSPAS...........QMLKTPQASITVktPASAA
 1461- 1481 (27.86/10.37)	KESK..MK...............FPGGAAAVkePPSPP
 1488- 1523 (22.32/ 6.51)	DSSISPAGisycfsglsdlQSVPWTELQTALtpPWS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.06|      49|     204|    1319|    1372|       3
---------------------------------------------------------------------------
 1319- 1372 (78.55/58.26)	PVGGcdanKNGFSSQAEL.AKHTADIHEpKEPL...IEDPLAW.ALESFRLGL.GLDAHG
 1525- 1579 (72.51/40.31)	PSGG....RGGSSAKSDKnSPRASDIGE.NDNLnisIAAERAWmPNEWFEDGAgGLEGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.39|      18|      32|     258|     275|       5
---------------------------------------------------------------------------
  258-  275 (35.73/19.62)	QNMTPE...QRQ.HLMNQNMDP
  287-  308 (23.66/ 9.88)	QFITAKasiQAQgHLRQGGLPP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13496 with Med15 domain of Kingdom Fungi
Unable to open file!