<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13477

Description mediator of RNA polymerase II transcription subunit 30
SequenceMWKYGQNQGNQGPAGAGGGGGGPNMMPMGGFGMQHGNMQQMHMSPQHQQQQQQQMGMMGGPGGMQMNPQGPGGPGGLMPGMSPQHPMQQQQQQMMQQQMMVPQQGVGVGVGVGVGMGGGVGMGGGGVVPQQQQPQQNMPQQNIPQQQQQLNPGGGIPPGGAGGNNNMLAISQQNPHKEINIVQLSRLGQETVQDIASRFQEVFASLKNIQPTSHRDNNTEKKVQEYFRTIRLLFKRVRIIYEKCNDAGMDYMSAESLIPYRDEPEPRIEPSQCDEYRKVLQENHELIETVKLKNRQLREIIDRTRIIIWEINTMLAMRRS
Length320
PositionHead
OrganismDrosophila ficusphila (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-0.794
Instability index69.10
Isoelectric point8.89
Molecular weight35333.91
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13477
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     215.73|      41|      41|      18|      58|       1
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   18-   58 (92.28/24.15)	GGGGGPNM...MPMGGFGM..QHGNMQQMHMSPQH..QQQQQQ..QMGMM
   59-  100 (69.43/16.49)	GGPGGMQM...NPQGP.GG..PGGLMPGM..SPQHpmQQQQQQmmQQQMM
  109-  151 (54.02/11.32)	GVGVGVGMgggVGMGGGGVvpQQQQPQQ.NMPQQN..IPQQQQ..QLN..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.01|      32|      57|     209|     243|       2
---------------------------------------------------------------------------
  209-  243 (45.43/42.18)	IQPtsHRDnNTEKKVQ...............EYFRTIRLLFKRVRIIYEK
  257-  303 (43.57/29.01)	LIP..YRD.EPEPRIEpsqcdeyrkvlqenhELIETVKLKNRQLREIIDR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13477 with Med30 domain of Kingdom Metazoa
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