<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13468

Description serine-rich adhesin for platelets isoform X15
SequenceMMMMDTMDTSQSQPMDVAPAVAVAATSGTALVDFTAAMVSMAATAEAESAESNNNHIGMAEYKEHRKNKKKKREKREREGKEHRHHKHRDREHREHRRHRDRDRERERESGGSHHHHPNNSQHSTSASSSPSSASTTPSATIEYVGGSASASPSYLGGGTAGTGGAVGATTTYPHNLKIRFLLSGQRTELSPPTHQTSATAEVNAPLASSSSASIAVTASATAASAPPATGSSTSGGSSSGNAGSTSSGNSSGGAAAGGAPSVVGSAAYPKTESSKSSGTGSAGGGSSSSSSSSKHGSSSKDISSNSSSQQPSTGSSSNAPSLYVSVPLSTANVPGINLPTSSSSSNTTSESHSASSRSSSAQSQHQQPSNLTTMGGASGAFHGGASSGGSSSVIQHQSGKSSPALGNLVSGNSGGSILSASGVPHPSGNLTATTTESGILKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHHHHHHPTHHNSHHQQNPQQQQQLHQQQQQSASSQQPHALHSSANSSSSSSTSTSTSSSSMSGGTVPATSSSTSTSKGPSRSGKKRGAAQSKNEAASVSTAATSSAVATTPAEKQSRHSSPHYNATPTPPPLSVAPPAVSSPVVMLQSLSSSSVDSPPATAAAASTTSRSTRNNSSSNANHNGDQTSSSCSSTSSSSSSGGSSGAASVVNLLDSPVNMSASSGSYRGSSNSTSNALPAGSQAKPLNKKMLRAQQTQLYQQQQQQQQQQQQQQQQQQQQQQQQQQQYAPPARSNSPTNLSSASASNSASFTHLQQQQQPQQQHEDLEILQFTNTNTTPSSNAPTSKPNNRTPDLSQASNSSSSAAAVPATTAPLMTLSSQLPLNSMAGGGGSTGGLKFTYESQTQLDVPMLPVSAIKDSPPSSPGSEVGSAMHTATLAASSLTAAAPTSAPAQPGNVRKRGRKAKDSTTAAATAAAAAAASAAVSNAQQDLKDVRLLQNGTASGSSNPASSTPTPPATPAASGTASSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTADALNSQYAGVPFPGKQRNSSAAISNAAPAPNPLQSMFSGGGINGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASSAKAEAHGK
Length1181
PositionKinase
OrganismDrosophila ficusphila (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.02
Grand average of hydropathy-0.721
Instability index69.14
Isoelectric point9.56
Molecular weight120701.83
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13468
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.43|      17|      17|      61|      77|       2
---------------------------------------------------------------------------
   73-   90 (31.96/17.46)	REKRErEGKE........HRHHKHRD
   91-  103 (26.58/13.38)	REHRE.............HRRHRDRD
  464-  486 (17.89/ 6.77)	RRSRS.RSGEsgsshhhaHHHHHH..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.22|      15|      17|     733|     747|       4
---------------------------------------------------------------------------
  733-  747 (33.32/14.62)	QQTQLY.............QQQQQQQQQ
  751-  765 (32.14/13.85)	QQQQQQ.............QQQQQQQQQ
  774-  801 (21.76/ 7.10)	SPTNLSsasasnsasfthlQQQQQPQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     188.55|      55|      56|     351|     405|       6
---------------------------------------------------------------------------
  344-  401 (86.02/25.26)	SSSNttsESHSASSRSS..SAQSQHQQPS.N.LTTMGGASGAFHGGASSGGSSSVIQHQSG...K
  402-  459 (49.35/10.04)	SSPA.lgNLVSGNSGGSilSA.SGVPHPSgN.LTATTTESGILKISYEKQ.TTRVQQLQEQ...E
  840-  897 (53.19/11.63)	SSSA...AAVPATTAPL..MTLSS.QLPL.NsMAGGGGSTGGLKFTYESQTQLDVPMLPVSaikD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.82|      32|      33|     223|     254|       7
---------------------------------------------------------------------------
  112-  146 (34.39/ 6.23)	GSHHhhPNNSQHSTSASSSP.sSASTT........PSATIEYVG
  237-  278 (38.43/ 8.13)	GSSS..GNAGSTSSGNSSGGaaAGGAPsvvgsaayPKTESSKSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.01|      27|      31|     898|     925|       8
---------------------------------------------------------------------------
  913-  944 (25.47/ 7.56)	TATLAASSLTAAAptSAPAQPGNvrKrGRK.......AK
  978- 1013 (28.54/ 6.12)	NGTASGSSNPASStpTPPATPAA..S.GTAssassiiTH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.25|      29|      33|     548|     578|       9
---------------------------------------------------------------------------
  148-  174 (29.51/10.32)	SASASPSYLGGGT.....A........................GTGGAVgATTtyP
  560-  591 (41.38/11.97)	SRSGKKRGAAQSKNEAASV.....................staATSSAV.ATT..P
  596-  647 (30.36/ 6.14)	SRHSSPHYNATPTPPPLSVappavsspvvmlqslssssvdsppATAAAA.STT...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.04|      15|     306|     220|     235|      10
---------------------------------------------------------------------------
  200-  214 (24.16/ 6.34)	TA.EVNAPLASSSSAS
  220-  235 (22.88/ 9.21)	SAtAASAPPATGSSTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.37|      26|     102|    1034|    1070|      12
---------------------------------------------------------------------------
 1034- 1062 (39.81/24.17)	SEQLHMEVQDHSIYTADALNSQyagVPFP
 1073- 1098 (48.56/21.86)	SNAAPAPNPLQSMFSGGGINGN...MPIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.51|      11|      15|      16|      26|      15
---------------------------------------------------------------------------
   16-   26 (18.50/10.62)	D.VAPAVAVAAT
   33-   44 (15.01/ 7.25)	DfTAAMVSMAAT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13468 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQQDLKDVRLLQNGTASGSSNPASSTPTPPATPAASGTASSASSIITHTAAHMLGNQINPNSSVAQKLSEQL
2) DVPMLPVSAIKDSPPSSPGSEVGSAMHTATLAASSLTAAAPTSAPAQPGNVRKRGRKAKDSTTAAA
3) MMMMDTMDTSQSQPMDVAPAVAVAATSGTALVDFTAAMVSMAATAEAESAESNNNHIGMAEYKEHRKNKKKKREKREREGKEHRHHKHRDREHREHRRHRDRDRERERESGGSHHHHPNNSQHSTSASSSPSSASTTPSATIEYVGGSASASPSYLGGGTAGTGGAVGATTTYPHNLKIRFLLSGQRTELSPPTHQTSATAEVNAPLASSSSASIAVTASATAASAPPATGSSTSGGSSSGNAGSTSSGNSSGGAAAGGAPSVVGSAAYPKTESSKSSGTGSAGGGSSSSSSSSKHGSSSKDISSNSSSQQPSTGSSSNAPSLYVSVPLSTANVPGINLPTSSSSSNTTSESHSASSRSSSAQSQHQQPSNLTTMGGASGAFHGGASSGGSSSVIQHQSGKSSPALGNLVSGNSGGSILSASGVPHPSGNLTATTTESGILKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHHHHHHPTHHNSHHQQNPQQQQQLHQQQQQSASSQQPHALHSSANSSSSSSTSTSTSSSSMSGGTVPATSSSTSTSKGPSRSGKKRGAAQSKNEAASVSTAATSSAVATTPAEKQSRHSSPHYNATPTPPPLSVAPPAVSSPVVMLQSLSSSSVDSPPATAAAASTTSRSTRNNSSSNANHNGDQTSSSCSSTSSSSSSGGSSGAASVVNLLDSPVNMSASSGSYRGSSNSTSNALPAGSQAKPLNKKMLRAQQTQLYQQQQQQQQQQQQQQQQQQQQQQQQQQQYAPPARSNSPTNLSSASASNSASFTHLQQQQQPQQQHEDLEILQFTNTNTTPSSNAPTSKPNNRTPDLSQASNSSSSAAAVPATTAPLMTLSSQLPLNSMAGGGGSTGGLKFTYESQT
966
886
1
1037
951
883










Molecular Recognition Features






MoRF SequenceStartStop




1) HHHHPTHHNS
2) LKIRFLL
3) LNKKMLRAQQTQLYQQ
4) RRSRSR
5) VRKRGRKAKD
483
177
725
464
936
492
183
740
469
945