<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13464

Description LOW QUALITY PROTEIN: uncharacterized protein LOC108097246
SequenceMESEQQDVGGGSGPLCRICITTHHQHNNSNTATTASRPMIPIFGEDALWQKITTLANVKISKNDTLPQQVCVGCAKTAISACVFKKKCEEADSFYRQQLRLQKIEGADPLESGSAAADQAKSSGCSSGSGSSSASGSGSSSTSSSSSSDDEDEDNDQDHDQDQDQAQEVEAGSEAHKRLQNGHGQTINGHRDDGDDEAPEGTGNIEEPEEGDRNGMEGANPEDGEDGEDVEEITPLNHHHNDDDGEITVHGVHPKEPYDFNSIRLMQEYMQHQMNKFPNGSATGPAGQEMDLDLDQQHRDDDDDDDDEDMSLPLIPEIELITPGDEAPADPSNPNDLVNGVGGVGVVAGMQGPGFQCPHCYQIFEMKQILKAHMQSVHGAPGPVYECSNCRKTYFYKRFLEKHIRRGRCVKKRRNQTRPMQCSDCHVLFPTGHHLGWHKRTGCPSKAAKMPLQQLFKQNIVQFNNFPKRIAGGGARKPAVPDLHVSNRKLGLANKRKGRTRIKLDAKKIALAKQLILREATTTVIANELNISRTFAWRLRKSLVNGVSLHERVVDPSQEQQDQHLQQLQQQQHHHHQQQLQQLHHHHQQQQQQQEEQQQQQQGAPAGEREHLNHLSLPYGHLGLGLIKEERQDSEDEDQQQQQQQQHHHHSHHPHHPLGLVDECGAEEIGAEETAGYMADEDAVCGLLHNGYDPDPDSDPIEHDPFEGTENNEHHLNGGGRPGSSSPAPQLQPGSLGGSSGVAGPGLQVHAAGRSDVEVYKRLLAESQHFPHIVNAQQLQLQQQHREREREREQREREREREQLQHQKAHNGGMPMLTRYPPAVMHALPVNLSLRSMPHMNSNESNGSSSSNTAAPVPVPGSSAAGSAATPTGKKPRKPNVFIDDEKYAMAKLLVAQNSSTMEIARALNVSQMTAWKVRDAILKGVPLSYRNKRSDGRHSEEFSAKEQQQHHQQQQQQQQQQQHQQQKEQQQRQQEMQRQQQQQLEQMELIKQQRQQQELLLQQQQQQQHQQQQQQQQQRHHATADTSHYQQQQQQQQPKMLHPRRRLKAAERELRDKEITREILELIKEDSNIQYWKVSARLAEKGINISPSSVCQKLKSMGIHRRWKPGDKPPMLAISQLKAATVAAAAAAASLAGVGGVVGGVVGGGGGGAGLASSSFGLTDDSFEQQQFDMGGPHFLSAFTR
Length1186
PositionKinase
OrganismDrosophila ficusphila (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-1.012
Instability index65.27
Isoelectric point6.04
Molecular weight131928.95
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro

GO - Biological Function
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13464
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     180.95|      20|      23|     946|     965|       1
---------------------------------------------------------------------------
  570-  586 (33.58/ 7.66)	QQ...QHHHHQQQLQQLHHH
  587-  605 (33.91/ 7.79)	HQ.QQQQQQEEQQQQQQGAP
  945-  964 (43.91/11.77)	AKEQQQHHQQQQQQQQQQQH
  965-  986 (33.11/ 7.47)	QKEQQQRQQEMQRQQQQQLE
 1007- 1022 (36.44/ 8.80)	QQ...Q.HQQQQQQQQQRHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.64|      29|      32|     347|     375|       2
---------------------------------------------------------------------------
  347-  375 (55.20/29.73)	VAGM..QGPGFQCPHCYQIFEMKQILKAHMQ
  377-  405 (52.74/28.09)	VHGA..PGPVYECSNCRKTYFYKRFLEKHIR
  410-  438 (41.70/20.72)	VKKRrnQTRPMQCSDCHVLFPTGHHLGWH..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     249.36|      76|     392|     442|     552|       3
---------------------------------------------------------------------------
  467-  552 (118.55/118.06)	PKRIAGGGARKPAVPDlhvsnrklglANKRKGRTRIKLDAKKIALAKQLILREATTTVIANELNISRTFAWRLRKSLVNGVSLHER
  856-  931 (130.82/68.63)	PVPVPGSSAAGSAATP..........TGKKPRKPNVFIDDEKYAMAKLLVAQNSSTMEIARALNVSQMTAWKVRDAILKGVPLSYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     141.52|      30|      32|     221|     251|       4
---------------------------------------------------------------------------
  161-  189 (35.33/15.77)	.QDQDQAQ......EVEAG.SEAHKRLQNGHGQ.TING
  191-  218 (29.47/11.78)	RDDGDD.EapegtgNIEE...P...EEGDRNG...MEG
  221-  251 (48.57/28.86)	PEDGEDGE......DVEEI.TPLNHHHNDDDGEiTVHG
  278-  304 (28.15/10.62)	PNGSATGP......AGQEMdLDLDQQHRDDDDD.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.85|      31|      31|     691|     721|       5
---------------------------------------------------------------------------
  659-  686 (35.85/13.28)	G.LVDECGAEEIGAEETAGYMADEDAVCG...
  691-  721 (54.85/24.21)	G.YDPDPDSDPIEHDPFEGTENNEHHLNGGGR
  723-  754 (43.16/17.48)	GsSSPAPQLQPGSLGGSSGVAGPGLQVHAAGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.10|      22|     392|     636|     658|       6
---------------------------------------------------------------------------
  636-  657 (47.57/15.22)	DEDQQQQQQQQHHHHSHHPHHP
 1026- 1047 (44.53/13.65)	DTSHYQQQQQQQQPKMLHPRRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.26|      15|      15|     112|     126|       7
---------------------------------------------------------------------------
  112-  126 (26.45/15.30)	SGSAAADQAKSSGCS
  129-  143 (25.81/14.75)	SGSSSASGSGSSSTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.84|      15|      15|    1073|    1087|       8
---------------------------------------------------------------------------
 1073- 1087 (26.44/16.61)	NIQYWKVSARLAEKG
 1089- 1103 (25.40/15.67)	NISPSSVCQKLKSMG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13464 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AILKGVPLSYRNKRSDGRHSEEFSAKEQQQHHQQQQQQQQQQQHQQQKEQQQRQQEMQRQQQQQLEQME
2) ALPVNLSLRSMPHMNSNESNGSSSSNTAAPVPVPGSSAAGSAATPTGKKPRKPNVFIDDEKYAM
3) LLQQQQQQQHQQQQQQQQQRHHATADTSHYQQQQQQQQPKMLHPRRRLKAAERELR
4) QLRLQKIEGADPLESGSAAADQAKSSGCSSGSGSSSASGSGSSSTSSSSSSDDEDEDNDQDHDQDQDQAQEVEAGSEAHKRLQNGHGQTINGHRDDGDDEAPEGTGNIEEPEEGDRNGMEGANPEDGEDGEDVEEITPLNHHHNDDDGEITVHGVHPKEPYDFNSIRLMQEYMQHQMNKFPNGSATGPAGQEMDLDLDQQHRDDDDDDDDEDMSLPLIPEIELITPGDEAPADPSNPNDLVNGVGG
5) SLHERVVDPSQEQQDQHLQQLQQQQHHHHQQQLQQLHHHHQQQQQQQEEQQQQQQGAPAGEREHLNHLSLPYGHLGLGLIKEERQDSEDEDQQQQQQQQHHHHSHHPHHPLGLVDECGAEEIGAEETAGYMADEDAVCGLLHNGYDPDPDSDPIEHDPFEGTENNEHHLNGGGRPGSSSPAPQLQPGSLGGSSGVAGPGLQVHAAGRSDVEVYKRLLAESQHFPHIVNAQQLQLQQQHREREREREQREREREREQLQHQKAHNGGMPMLTRYPP
921
827
1001
98
548
989
890
1056
343
822










Molecular Recognition Features






MoRF SequenceStartStop




1) IHRRWK
2) LPLIP
1104
312
1109
316