<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13454

Description mediator of RNA polymerase II transcription subunit 28
SequenceMTSNEPGGGNLMDEFEEAFQSCLLSLTKQEPNSGTNKEEIELEVQKTTNRFIDVARQMEAFFLQKRFLVSTLKPYMLIKDENQDLSIEIQRKEALLQKHYNRLEEWKACLSDIQQGVHSRPTPPIGAGMLQGPGGGMSPMGGVPPRPGMMPGIPPGAMQPGGPMQPSPQHMLQAQQMQQLRMMGKLPPK
Length189
PositionHead
OrganismDrosophila ficusphila (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.611
Instability index71.41
Isoelectric point6.32
Molecular weight21015.11
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13454
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.57|      21|      25|     116|     139|       1
---------------------------------------------------------------------------
  116-  132 (17.17/ 8.15)	.........GVHSRPTPpigAGMLQG
  133-  152 (36.80/12.02)	PGGGMSPmgGVPPRP......GMMPG
  154-  173 (39.60/13.38)	PPGAMQP..GGPMQPSP...QHMLQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.12|      20|      22|       1|      20|       2
---------------------------------------------------------------------------
    1-   20 (36.66/20.19)	MTSNEPGGGNLMDEFEEAFQ
   26-   45 (33.46/17.91)	LTKQEPNSGTNKEEIELEVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.45|      17|      22|      73|      90|       3
---------------------------------------------------------------------------
   73-   90 (25.45/24.54)	KPYMLIKDENQDLSiEIQ
   98-  114 (31.99/25.04)	KHYNRLEEWKACLS.DIQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13454 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SDIQQGVHSRPTPPIGAGMLQGPGGGMSPMGGVPPRPGMMPGIPPGAMQPGGPMQPSPQHMLQAQQMQQLRMMGKLPPK
111
189










Molecular Recognition Features






MoRF SequenceStartStop




1) LMDEFEE
2) LRMMGKLPPK
11
180
17
189