<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13447

Description mediator of RNA polymerase II transcription subunit 27
SequenceMDKLNSTLTAVKNLRSNVRQCFEHLADGTDGEGVEESRNKFVHDFQERFGAINSQLREVEQLINGLQVPPTAYSLGNTAYLAQETSHDRQALYPQLVNSYKWIDKVHEHSFLAFNNLNQNTLRRSYNYCSQKRQRLPFSSFNNDPDHIDKLLSEINTPPHTSYRIFRPFGTNAVAIVTISNVMKAAIVFKGVLIEWVTVKGFDEPLEHDDLWAESRYEVFRKVQEHAHSAMLHFFSPTLPDLAVKSYVTWLNSHIKLFLEPCKRCGKFVVHGLPPTWRDLRTLEPFHEECRNC
Length293
PositionTail
OrganismDrosophila ficusphila (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.11
Grand average of hydropathy-0.475
Instability index37.50
Isoelectric point6.92
Molecular weight33934.98
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13447
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.55|      17|      25|     249|     265|       1
---------------------------------------------------------------------------
  249-  265 (34.32/18.21)	TWLN.SHIKLFLEPCKRC
  276-  293 (31.23/16.09)	TWRDlRTLEPFHEECRNC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.73|      21|      25|      96|     116|       2
---------------------------------------------------------------------------
   96-  116 (39.29/32.85)	LVNSYKW.IDKVHEHSFLAFNN
  122-  143 (34.44/27.82)	LRRSYNYcSQKRQRLPFSSFNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13447 with Med27 domain of Kingdom Metazoa
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