<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13410

Description Uncharacterized protein
SequenceMACAEFSFHVPSLEELAGGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPNLARLAQRIDFSQGSGSEEEEAAGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATEKQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL
Length838
PositionHead
OrganismHomo sapiens (Human)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Homo.
Aromaticity0.07
Grand average of hydropathy-0.343
Instability index53.32
Isoelectric point7.82
Molecular weight93444.04
Publications
PubMed=16554811

Function

Annotated function Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13410
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     214.38|      70|     339|     175|     435|       2
---------------------------------------------------------------------------
  362-  435 (111.09/286.70)	QENKLQrDFnsELLRLRQHwKLRKVGD..KILG..DLSYRSAGSLFPHH..GTFEVIKNTDLDLDKKI.....PEDYCPLDVQIP
  704-  784 (103.29/15.24)	QEQELQ.DF..LLSQMSQH.QVHAVQQlaKVMGwqVLSFSNHVGLGPIEsiGNASAITVASPSGDYAIsvrngPESGSKIMVQFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.11|      30|     181|     477|     506|       4
---------------------------------------------------------------------------
  477-  506 (52.15/36.41)	HW...QTKLEAAQNVL........LCKEIFAQLSREAVQIK
  650-  690 (40.96/27.06)	HWsniNDVYESSVKVLitsqgyeqICKSIQLQLNIGVEQIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.78|      39|     669|     114|     155|       5
---------------------------------------------------------------------------
  114-  155 (61.50/46.18)	EKCHDFQCA..LLANLFASEGQPGKviEVKAKRRTGpLNFVTCM
  786-  826 (70.28/41.88)	NQCKDLPKSdvLQDNKWSHLRGPFK..EVQWNKMEG.RNFVYKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.85|      20|      20|     239|     258|       7
---------------------------------------------------------------------------
  239-  258 (35.51/16.96)	GSGSEEEEAAG.TEGDAQEWP
  261-  281 (32.34/14.93)	GSSADQDDEEGvVKFQPSLWP
---------------------------------------------------------------------------











Associated diseases
Disease


























Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13410 with Med17 domain of Kingdom Metazoa
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