<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13386

Description Uncharacterized protein
SequenceMHPIVTGTDAIGDRVTLCLNEHRFLAYKLLDALSHASSNTTPSILRTTDSLFEDVLKKDRVLLQTIKQLNQHQRAQKELDRIKQQIAEKEAKIVAYAKELRTGQQAINSVLLKHKRVLENAKAAPNTPRFPPQDIIAYAHKVASTTSAALNWQPGFAMVGFLPPAPTPEMMRAGVLSRGIIDSLVTKESTAYTATKRPIEDITAPTPLTGEVRINLGTSDEEIEKLFPAGWKAGDAIDLPAEALVRHRGAAIFADYGIEIPANMLKTGNDYLSVPQTYMDQLRAKLEEKNAGHIDKKQRVDDEDSSGSSSSSENDEGYYYLLLTLHHSNALDRMGRTRNRKKHPEFNCHYRTRKMMINYLDMTLKQNAMNIEAKIDFLVGTQNTIFADLMTSNCSASGLLTPDSSKCLALTSKNIAYVTSSSLTSTSTAAVNSALQKAQAASKQATLMLVKCVDDVRGYDQLWFQNSLQSIATFACDSMLSSAEKERCVPIGNSAAVLNGSLCQRVSGNGNCFDQGLCERAANCYWPPPANDREPYYSAADISAAKDWVTHSYPNSFVPFAIPGVFLACIVLLSMVVFLILRCGCNRCYGRNPHRHGYTKLQRVVPITVFGLFTIGIILCAAFAFTQNQVITDGINGSFDAIDMALSNLDTMTNNIDSPLEMISSTVNSTVSQITKQLNPANTSIWMASDMATLQKLTSTFTNRLSSLGPFPLGCTTGGSDVCVSCPAALCSSIPSALTTTMQSLSSSQSAILTIVTTMYNNLQQSQSTIESALSDAATLLGYVQTKATSTQSNLRSAYTSFTSVSSVQIAALLAAFALGLFVCFLGIIGIITGVCSRTCCLIRILNLSWFLGALVCILGFILSAVILIIAMMGNDMCHYVNVLHDNSSAVWPGQMSEILQSCFQNTSLLNALDIDSELSFSCTLEDKFTITNSLNFTPLTAAMTTLSTDLLSIDETTWFSQSPEQLVNEAKAYIPNLTLQNLPTPWKAYGYASLSATGETSCYSASTTVAPRCYMNIKCNGGSTSCYASYVAAYDTYLAEQQIHDSLVELNADFSAATSQHSAGWNTSYVSILNYMTTYTDALTQLNYNVLAPLKSGVVGDILKRVDQMKCSMTCRWLNASYNLLYDSVCSNLVGSTLIISLCIFLMCLFLLPIIFMEIVLEKRLRGLRKESEKKSNAAKPIPSTQA
Length1188
PositionMiddle
OrganismThraustotheca clavata
KingdomOomycetes
LineageEukaryota> Sar> Stramenopiles> Oomycota> Saprolegniales> Saprolegniaceae> Thraustotheca.
Aromaticity0.08
Grand average of hydropathy0.031
Instability index42.89
Isoelectric point6.46
Molecular weight129644.09
Publications
PubMed=25527045

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13386
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.10|      30|      34|     800|     829|       1
---------------------------------------------------------------------------
  800-  829 (48.24/30.89)	TSFTSVSSVQIAALLAAF.ALGLFVCFLGII
  833-  862 (58.10/38.83)	TGVCSRTCCLIRILNLSW.FLGALVCILGFI
 1112- 1131 (23.76/11.16)	...CSMTC...RWLNASYnLLYDSVC.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.65|      31|      34|     635|     666|       2
---------------------------------------------------------------------------
  631-  662 (46.88/32.99)	ITDGINGSFDAIDMALSNLDT...MTNNIdSPLEM
  663-  696 (44.77/26.54)	ISSTVNSTVSQITKQLNPANTsiwMASDM.ATLQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.45|      17|      34|     992|    1017|       3
---------------------------------------------------------------------------
  999- 1016 (30.97/30.37)	GETSCYsASTTVAPRCYM
 1023- 1039 (33.48/ 9.11)	GSTSCY.ASYVAAYDTYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.72|      33|      36|     205|     240|       4
---------------------------------------------------------------------------
  166-  203 (45.65/29.58)	PTPemMRAGV.LSRGIIDSLVTKestAYTATKRPIEDIT
  205-  238 (53.06/50.64)	PTP..LTGEVrINLGTSDEEIEK...LFPAGWKAGDAID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.06|      11|      36|     320|     331|       5
---------------------------------------------------------------------------
  320-  331 (15.98/16.35)	YLLLTLHHsNAL
  359-  369 (21.08/15.30)	YLDMTLKQ.NAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.13|      29|      34|     732|     764|       6
---------------------------------------------------------------------------
  732-  764 (43.51/36.73)	SSIPSALTTTMQSLSSSQsailTIVTTMYNNLQ
  768-  796 (46.62/29.63)	STIESALSDAATLLGYVQ....TKATSTQSNLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.76|      15|      36|     913|     927|       7
---------------------------------------------------------------------------
  913-  927 (26.03/11.69)	LDIDSELSFSCTLED
  952-  966 (25.73/11.48)	LSIDETTWFSQSPEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.53|      16|     288|     136|     151|       8
---------------------------------------------------------------------------
  136-  151 (27.44/18.17)	IAY..AHKVASTTSAALN
  415-  432 (22.09/13.01)	IAYvtSSSLTSTSTAAVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.76|      38|     288|     573|     628|       9
---------------------------------------------------------------------------
  551-  575 (32.99/33.76)	.......HSYP..NSFVPFAIPGVFLACIV..........lLSM
  589-  628 (50.41/37.46)	YGRNPHRHGYTklQRVVPITVFGLFTIGIILCAAFaftQN....
  880-  909 (54.37/24.39)	YVNVLHDNSSA....VWP....G..QMSEILQSCF...QN.TSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.17|      27|      34|      49|      75|      11
---------------------------------------------------------------------------
   49-   75 (40.73/32.41)	DSLFEDVLKKDRVLLQTIKQLNQHQRA
   80-  106 (38.33/30.03)	DRIKQQIAEKEAKIVAYAKELRTGQQA
  108-  129 (22.10/13.88)	....NSVLLKHKRVLENAKAAPNTPR.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13386 with Med4 domain of Kingdom Oomycetes
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