Description | Mediator of RNA polymerase II transcription subunit 21-like |
Sequence | MADRLTQLQDSVNLQAENFCNSIGVLQQLAQPSPFPELEKSSKSTPQPQEDYAALFATMIARTAKDMDVLIDSLPSEEAAPELQNAIVDVRRNEVFDLSRPK |
Length | 102 |
Position | Middle |
Organism | Tropilaelaps mercedesae |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Mesostigmata> Gamasina> Dermanyssoidea> Laelapidae> Tropilaelaps. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.425 |
Instability index | 76.84 |
Isoelectric point | 4.38 |
Molecular weight | 11333.61 |
Publications | PubMed=28327890 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP13381 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) DRLTQLQD 2) ENFCNSIGVLQQLAQPSPFPELEKSSKSTPQPQEDYAALFATMIARTAKDMDVLIDSLPSEEAAPELQNAIVDVRRNEVFDLSRPK | 3 17 | 10 102 |
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