<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13359

Description Mediator of RNA polymerase II transcription subunit 24-like
SequenceMMLTNCGDRCRGTNEISCPIVCKPLVSRYVPFFLFYKMDTSKTSSIKSLLMQAWRERWSDVLWGINIKNVLPRGVSGDVYDLADCILQQALVGPGPNQLFMSYLTHCLSSQVISYGATFSSVARFDSLHKAQCLQSLLDLVAGMEQRVVCPGNEEECIALCKSTVSITLWLYNCMLYAAAKQEPPYAQVLEKSASSLAFFSQDTFLKALLYIGRCEEKDAYQAVLERQAEAQQKLAGIQGAARETVDAALSLVNRLDEMNRIPSEQSPRKPGAVIGLVANVTVEAILNPCNSADSVADALQLTRKLLNIPGPVFYSEIIRSCVMGLSDSSQQLNNLRWSEFTFLKLPVILDKIGKSDPDLLTGVDMVLSCKSLLNAADEKCSIDCLGLIVSELSKVGVISDAEAQLIRARRQSRHKSDGPKEGPSPAPIMILRAEPTVQNVLGMLDNGCNPEALLSVLTQMLRESKFELIVSAAVGTDKLNVLVQKLININNQNNAFVAEGGETRAVLFDITFLMLCHIAQTFGVDAVVREETKDSVFAQWLPDCLVHPNRYTCPTKFLSKANPDKVELLLHQMLSAGEKNEPLDFRTTHLQWSDLLYDVPAAVKEILKGWQEEVLAMHMVKSIMEQIKSKMCFPAVCTSAWLSCYINTLHCNDQLKPKNVMLIFSLANVDDSSGVLDYYKYAQEMMVSIVKKMMYYHATSSSQKGQKNTSALIEKTPLWTAVEEIFDNVHSGAWIDITTINSLNGILDTVGPVWFCDALIRHALKYQHQDDLNCAIELAYGLFQIDVQLCALALLTNVLPNYLLWESKQDFLTEPKGSALAKLVTLTTFTALTLRPAKGGGAPESRKTYPVWEMRLQESLLNHSKSRNKNRRMNTDLESLEDTPYGLQFHNNEDSLEPLDRAIAELFRLLYAIATEPVISQRSFFPLELFRQFVTCGDPGVASQVLQFLPLGFISQLVRAMPQSLSPSLVLALSSFTTPRTRKVVARAICQLQITQAMT
Length1000
PositionTail
OrganismTropilaelaps mercedesae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Mesostigmata> Gamasina> Dermanyssoidea> Laelapidae> Tropilaelaps.
Aromaticity0.07
Grand average of hydropathy0.017
Instability index47.28
Isoelectric point5.94
Molecular weight111222.50
Publications
PubMed=28327890

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13359
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.26|      17|      21|     919|     935|       2
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  919-  935 (32.26/22.55)	VISQ.RSFFPLELFRQFV
  942-  959 (24.00/14.74)	VASQvLQFLPLGFISQLV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     196.98|      51|     278|      57|     132|       3
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   57-  108 (85.52/55.83)	RWSDVLWgINIKNVLPR.GVSG.DVYDLADCI.LQ.QALVG.PGPNQLFMS.YLTHCL
  281-  323 (45.30/20.47)	........VTVEAILNP.CNSA.D..SVADALqLT.RKLLNiPGP..VFYSeIIRSCV
  337-  390 (66.16/49.90)	RWSEFTF.LKLPVILDKiGKSDpDLLTGVDMV.LScKSLLN.AADEKCSID.CLGLIV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.89|      17|      95|     634|     650|       5
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  634-  650 (34.10/23.51)	FPAVCTSAWLS.CYINTL
  727-  744 (27.79/17.77)	FDNVHSGAWIDiTTINSL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.23|      33|     103|     753|     785|       7
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  753-  785 (62.56/43.68)	PVW...FCDALIRHALKYQH....QDDLNCAIELAYGL.FQ
  851-  891 (44.67/28.98)	PVWemrLQESLLNHSKSRNKnrrmNTDLESLEDTPYGLqFH
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.02|      26|     137|      10|      38|       8
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   10-   38 (43.32/43.40)	CRGtNEISCPIVCKPLVSryVPFFLFYKM
  150-  175 (52.70/38.13)	CPG.NEEECIALCKSTVS..ITLWLYNCM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13359 with Med24 domain of Kingdom Metazoa
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