<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13356

Description Mediator of RNA polymerase II transcription subunit 26-like (Fragment)
SequenceMTKSMMHRGGRATTISEKVGLCMRFSVQHGPDLRSRLPFICRSVRRISEGRRCFDGTQQKLSFAPSHLSHLAMCQDGRGWLRADLSLGEAATITAMTYRDSTQQTTILTVHRTEDFSKLKAGQAYKASVSDAGAEFWLRLFRFPCSFEVGFAHESHGTRFNSLREVVDMVAVLDCISLLESLPIRREDLERTRLGRVVNELRKKTSDVALQRRAKDLVRGWRKLLDENPPSVGLGSTPNGTAQHPHAPHTPLTHHAAQKVSSPALSASAAATPATPLGASHGAHGGVQTRVAQLQMQSGVAGAGGHGRITSPASSVSNSPVLRTRNGSGFKPVSPAVPTGSPSPNAVAPLASHAASGGSGQTA
Length363
PositionUnknown
OrganismTropilaelaps mercedesae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Mesostigmata> Gamasina> Dermanyssoidea> Laelapidae> Tropilaelaps.
Aromaticity0.05
Grand average of hydropathy-0.335
Instability index43.93
Isoelectric point10.45
Molecular weight38771.52
Publications
PubMed=28327890

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13356
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.23|      38|      54|     249|     302|       1
---------------------------------------------------------------------------
  249-  286 (70.17/46.18)	HTPLTHHAAQKVSSPAL.....SASAAATPATPLG..........ASHGAHGG
  306-  358 (56.06/18.27)	HGRITSPASSVSNSPVLrtrngSGFKPVSPAVPTGspspnavaplASHAASGG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13356 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) NPPSVGLGSTPNGTAQHPHAPHTPLTHHAAQKVSSPALSASAAATPATPLGASHGAHGGVQTRVAQLQMQSGVAGAGGHGRITSPASSVSNSPVLRTRNGSGFKPVSPAVPTGSPSPNAVAPLASHAASGGSGQTA
228
363

Molecular Recognition Features

MoRF SequenceStartStop
NANANA