<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13354

Description Mediator of RNA polymerase II transcription subunit 23-like
SequenceMGSIDAVNSLVGAILRRDALEEAFNAFIVHKDSPGGQGGGSNAGLVEELSAVLSTPTDTSDAALRAFVTLATQLRSHKQLAKLLSILEQTANEGKVNSRQVCEALMGGLDFQQAEFWVQALGLVERLLPKLDYKGCRDVLKLIFEKSQQIPSTVNLSCMRQLQVLESVAELLLDRDQALCPSYLVLDDVQKRLDWPHWKIARLVSSFVDSFRPVAQLVTIVGRSRLVPVVGHSAASGYSWQIDRVHARFSLKGQLPYSSEATRSQTNLLRYVLAQPYSREMVCAMLGLNKQQKQRCVVLERQLIELIVAAMQRSETEPLNSESLCQFWQNISSQLIYFVLFQYISFPDLVIGLHTQLAASPLRKGRDQLMWVLLQFISGSIQKNSLNDFLPVLRLYDLLYPESEPLPFPDVTDPSCTHKLAVTCIWVHLMKKAQGERGMQRPVPQALSVHLETLQQALSQHQTSDYWTSLLCNAYSTNVECFSRPMGVLVEAIQGGAGGHATATQPLSMGMLDSLTVHTKMSLIHNIVTYFMKVYNEIESLGIKGFMSHVLPLAFRQQAWAILHTLLEMFSYRLHHIQPHYRIQLLSHLHMLASVPQSNQAQLHVCMESTALRLITGLGSGEVQPQLSRFQAEPKSLLSLDSEELNKALILSLARAIHVTGSESLSTVWCKDLLQAALANTPHSWSSLTLDCFPNSLAEFLRVNQAQRENKAQLKRSVEEEYRKWKTMSNENDIVAHFSQSPSTGGQASGGSASPHLFICLLWKMLLENDRISPLAYKILDRLGARALSLHLRTFADFLVYEVSTCGQDQMLMINKSIDAVNDLIWKCYVIPLDRLILTLALRPFEGNEQQVGFFIIQRLLISNGEFKSRVYDFVKENSPEHWTQSDWHERHQQFQRKYPEKFYWENLPDSSQPHHYLPVYFGNICLRFLPVMDIVIHRLIELPMNTSSSVSVESMLDHLGVLYRFHDRPLTYLYNTLHYYESKLRDRFGLRIKLVSAITARMNEYPLSNYFRQLIVHQQQQQPQQQSPQDQQARPGESSLANQAVNAPSTNIPPPDMDYYRFILQRMVDVMAGKKTSPVIDWSRAPYNFLYYSGIHRFNEFSNGAAHTLHVTCIELMALPVAPAAVANGLLNVILLGHSHNVVSRDALPDWINAIGLVLTALPESYWAVLNDRILHLIETLPPTTDIFQYMDLAGKQKSYTESSTSYVVALVHAVWYHASIGQLSQIPVFIKDRLKPVIRTEEQMLVLCQLVAPFFQRISLERTRSLMEITRELYEILENVDKAQNELRYMDNIVDLFYHIKYMFTGDSVKADVDHVIRNLRPALQLRLRFITHLNVGAQAETAGASGSDGQAISASAGNSAQGQQAMGTTPGQGVGNVSQS
Length1383
PositionTail
OrganismTropilaelaps mercedesae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Mesostigmata> Gamasina> Dermanyssoidea> Laelapidae> Tropilaelaps.
Aromaticity0.09
Grand average of hydropathy-0.097
Instability index48.03
Isoelectric point6.80
Molecular weight156090.50
Publications
PubMed=28327890

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13354
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     240.22|      82|     308|     686|     780|       1
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  686-  780 (114.23/99.69)	SSLT..LDCFPnsLAEFLR...VNQAQRENKAQlkrSVEEEyrkwKTMSNENDIVAHFSQSPSTggQASGGSASPHLFIclLWKM..LLENDRISPL......AYKIL
  997- 1091 (125.99/73.42)	SAITarMNEYP..LSNYFRqliVHQQQQQPQQQ...SPQDQ....QARPGESSLANQAVNAPST..NIPPPDMDYYRFI..LQRMvdVMAGKKTSPVidwsraPYNFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.17|      28|     310|     276|     335|       2
---------------------------------------------------------------------------
   78-  117 (39.12/ 8.60)	KQLAKLLSILEQTANEGKVNSRQVCealmggldfqqaEFW
  301-  328 (49.05/14.18)	RQLIELIVAAMQRSETEPLNSESLC............QFW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.45|      28|     310|     596|     642|       3
---------------------------------------------------------------------------
  557-  584 (53.86/28.96)	QQAWAILHTLLEMFSYRL......HHIQPHY.RIQ
  597-  631 (39.58/51.50)	QSNQAQLHVCMESTALRLitglgsGEVQPQLsRFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.23|      39|     309|     918|     994|       4
---------------------------------------------------------------------------
  158-  196 (69.89/35.21)	CMRQLQVLESVAELLLDRDQALCPSYLV...LD..DVQKRL.DWP
  926-  970 (55.34/91.38)	CLRFLPVMDIVIHRLIELPMNTSSSVSVesmLDhlGVLYRFhDRP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13354 with Med23 domain of Kingdom Metazoa
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