<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13346
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MNTRLQSSYHTLEQALQRLTDSIATYNPNLTYADQLVTANDAVDRDLELLATHQSNYARIQSLRAQSTALDSSLRSTISQLAQTRKDILAIPPAPSPSSIDQSNELNVDTLLRYAALIAPTTVPPTLRKPIPSIQLPRVKLEGDGSVERVGGLSTPPPQPEGEQGDVKEGIVGIERVGELERGWLAGNGDVGFVPWVSDEAIRGGALAKLEGVGEGSREGKRMEVDQQEDGRVTDEARAEQEEQDRRRRRERARAEVRVFNPDDL |
Length | 265 |
Position | Middle |
Organism | Rachicladosporium sp. CCFEE 5018 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Cladosporiales> Cladosporiaceae> Rachicladosporium>
unclassified Rachicladosporium.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.648 |
Instability index | 55.77 |
Isoelectric point | 4.92 |
Molecular weight | 29125.00 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13346
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
4| 138.17| 27| 66| 140| 166| 1
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105- 138 (25.03/10.86) ELNVDTLL.RYAALiaptTVPPtlrkPIPSIQLPR
140- 166 (49.29/28.15) KLEGDGSVERVGGL....STPP....PQPEGEQGD
185- 205 (27.25/12.44) .LAGNGDV....GF.....VPW....VSDEAIRGG
209- 235 (36.61/19.11) KLEGVGEGSREGKR....MEVD....QQEDGRVTD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 123.24| 33| 64| 3| 35| 2
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3- 35 (55.34/34.34) TRLQSSYH.TLEQALQRLTDSIA.TYNPNLTYADQ
38- 61 (24.03/11.35) .........TANDAVDRDLELLA.THQSNYARIQ.
68- 102 (43.87/25.91) TALDSSLRsTISQLAQTRKDILAiPPAPSPSSIDQ
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