<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13228

Description Uncharacterized protein
SequenceMAPVTLKTVDDDLKDVIQHLFEIQSAVHGYLGPETQQELVRKIKNLTLALSTLSTHTQLPPTQENQPETNTDPSNPSLASIQLPPEIIDYVDSARNPDIYTREFVELVQRGNQDLRGKREAFASFRDVLAREMRSAMPECRGEVDRVVAATGGAVDGPDGVPGAAATSGGQLEPLNLAAGKLDFDGVDPEAGMHLLSIYWSRQLYTAQIIYRPAFMRDMACEGPYFSKLLLNAIFFVTSKHCDRPELRSDPNDITTAGWKFRQRFTQLLRDCFDKSEITTLQALLIMSNALFSRCDERSLSWLYAGNAFNMFIDLGLHVLPAVDSISAEELEIRKRVLWGAYLIDKIQCLFQGRPPLLNRVNLRASLDFLDDYDELEPFQGITYMTTKPREVIPSMNVSLLTNLCKLTTIVERVLREIYSESRESNLVHRANISEEIKSQLRIWRQSLPDQLDYLSFPDQAVLLPQSACLLALFNVLIILVHRPLIIGHDGITNSTTAHESVNACTAAANQIVQILHDYSQHFSLSSAPYMLSYATYISATVHARIVAQKGSNSTVFQSLVLCRNILCEHTRLYSAAEKARENLDKLIFHLGISVADDNQHTGTPGSSAGNFPNEHMVIDESINVAREISVADPAPELGSSLMSLELSDLDLEAIAQGFQVDVESHSFWNSLV
Length673
PositionMiddle
OrganismPenicillium vulpinum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium.
Aromaticity0.07
Grand average of hydropathy-0.125
Instability index40.13
Isoelectric point5.10
Molecular weight75050.38
Publications
PubMed=28368369

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
DNA binding	GO:0003677	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13228
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.66|      20|      27|      36|      61|       4
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   36-   61 (23.99/28.15)	QQELVRKIKNLTLAlsTLsthtQLPP
   66-   85 (37.67/22.28)	QPETNTDPSNPSLA..SI....QLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.51|      11|      27|     199|     211|       6
---------------------------------------------------------------------------
  199-  211 (17.82/16.64)	YWSRQLYTAqiIY
  225-  235 (19.69/11.02)	YFSKLLLNA..IF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.70|      17|      20|     144|     163|       7
---------------------------------------------------------------------------
  144-  160 (29.06/18.74)	VDRVVAATG....GAVDGPDG
  172-  192 (23.65/ 6.88)	LEPLNLAAGkldfDGVDPEAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.54|      12|      23|     415|     427|      10
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  415-  427 (15.86/13.03)	LReIYSESRESNL
  441-  452 (22.68/13.77)	LR.IWRQSLPDQL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13228 with Med10 domain of Kingdom Fungi

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