Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MFGKANQSVPPPGRRANKGEEKRAAGRKWRAGGCAEGISAGRYFSLAKMGEPQQVSALPPPPMQYIKEYTDENIRKGLAPKPPPPVKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILVNFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQNCLASLPDDLPHSEGGLRVKVETMDADDGSSCTGQSEKQRERSGGKRDQVLDKDAAMCSIIDEMT |
Length | 278 |
Position | Middle |
Organism | Patagioenas fasciata monilis |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Patagioenas. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.705 |
Instability index | 52.71 |
Isoelectric point | 8.51 |
Molecular weight | 31699.13 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP13147 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 36.71| 10| 47| 3| 12| 1 --------------------------------------------------------------------------- 3- 12 (20.29/10.00) GKANQ..SVPPP 50- 61 (16.41/ 6.99) GEPQQvsALPPP --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 136.77| 44| 77| 107| 152| 2 --------------------------------------------------------------------------- 107- 152 (64.91/48.85) LESQGIERLHPMQfDHKKELRKLnMSILVNFL.DLLDILIRSPGSIK 187- 231 (71.86/44.52) MEVQKRQRLETAE.RFQKHLERV.VEMIQNCLaSLPDDLPHSEGGLR --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) ANKGEEKRAAG 2) QYIKEY | 16 64 | 26 69 |
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