<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13144

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMSRIVEGASVSVVCPLLYPSPTSKSSIVGDKNAFQTWAGKAGEKIHNMVAVLEVISSLEKYPITKEALEETRLGRLINEVRKKTSNEELAKRAKKLLRNWQKLIEPVTQSEAVPRGLPNPPGSANGGAHNCKAEAQLSAVAAAKPISELKSRNDIQKLNSPKTEKLGNRKRKGEHRDGHQGPPPPKVSKASHEVLQNSSPPPTNGIGGSPENFPSPVDVNVHAGPEGSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEETTGPHQPKSPRCSSFSPRSVRHDTFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFPQQSAPEAPQPWQEQQVPADAQHRHPAGTLQPHTAPGCKTGSHPSESLPPHTGFPQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVIEGGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALAEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRIREHNWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length633
PositionUnknown
OrganismPatagioenas fasciata monilis
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Patagioenas.
Aromaticity0.04
Grand average of hydropathy-0.922
Instability index59.84
Isoelectric point9.00
Molecular weight69731.26
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13144
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.67|      12|      16|     378|     389|       1
---------------------------------------------------------------------------
  334-  345 (21.74/ 6.95)	PPPSLMQPSTPP
  378-  389 (24.93/ 8.97)	HPAGTLQPHTAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.47|      16|      22|     486|     505|       3
---------------------------------------------------------------------------
  472-  487 (22.85/ 6.34)	TQKDPLQVEIPALAEQ
  492-  507 (27.63/20.28)	TEKQEQKPNLQSPFEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.80|      24|     149|     390|     413|       5
---------------------------------------------------------------------------
  254-  275 (29.30/ 9.42)	GLVKPSSTSSLL..KTAVLQQHDK
  277-  299 (37.89/14.14)	EETTGPHQPKS.PRCSSFSPRSVR
  390-  413 (44.61/17.82)	GCKTGSHPSESLPPHTGFPQDASK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.07|      18|      22|     430|     451|       8
---------------------------------------------------------------------------
  430-  451 (24.82/25.69)	RYRPRDYTvnLDGhvIEGGVKP
  453-  470 (33.25/19.12)	RLKERKLT..FDP..MTGQIKP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13144 with Med26 domain of Kingdom Metazoa

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