<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13139

Description Transcription elongation factor A protein 1 isoform A
SequenceMTTEDEIIRIAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCREMLSAALRTGDDYIAIGADEEELGSQIEEAIFQELKNTDMKYKNRVRSRIANLKDAKNPNLRKNVLCGNIPPDKFAKMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Length303
PositionUnknown
OrganismPatagioenas fasciata monilis
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Patagioenas.
Aromaticity0.04
Grand average of hydropathy-0.818
Instability index54.03
Isoelectric point8.76
Molecular weight33882.17
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13139
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.60|      24|      27|      83|     109|       1
---------------------------------------------------------------------------
   85-  109 (35.48/29.61)	DKDSEEKKKEpASSSQNS..PE.AREES
  111-  137 (33.12/15.33)	SSNSSSRKEE.GSAPSNSfiPSfPRAPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.75|      18|      27|     207|     224|       2
---------------------------------------------------------------------------
  190-  204 (17.77/ 7.34)	...KNRVRSRIANLKDAK
  207-  224 (31.66/17.40)	NLRKNVLCGNIPPDKFAK
  237-  254 (29.31/15.69)	EMRKNLTKEAIREHQMAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.45|      14|      27|     260|     273|       3
---------------------------------------------------------------------------
  260-  273 (28.18/16.53)	TDLFTCGKC..KKKNC
  288-  303 (25.27/14.20)	TTFVVCNECgnRWKFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.41|      34|     146|       1|      38|       4
---------------------------------------------------------------------------
    1-   38 (50.19/43.97)	MTTEDEIIRIAKKMDKMVQKKNAAgaldLLKELKNIPM
  154-  187 (56.23/38.50)	LRTGDDYIAIGADEEELGSQIEEA....IFQELKNTDM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13139 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCRE
78
148










Molecular Recognition Features






MoRF SequenceStartStop




1) IRIAKKM
2) LIKSWKKLLD
8
71
14
80