<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13124

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMEPPEPAGRCRGKVAAMKVVNLKQAILQAWKERWSDYQWAINMKKFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAVYAERVKETLEQAAAESQLKLCLERLEKMLSSTKNRALIHIAKLEETSSWSAVEQSLVKLGENLSSLSNSPLRSQADNCISLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQLLVEQLMMVKRMQRIPSPLFILEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGDKDFTEDVNSAFEFLLKLTPLLDKADQRCNCNCMSLLLQECSKQGLLSEANMENLSEKRQADREHAPHLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSTSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHITGEGSKGAPVRALLFDISFLMLCHVAQTYGSEVILSESSPAGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMVVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLHSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPNRSMSTSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPRIVLAITDLSLPLGRRVAAKAIAAL
Length1002
PositionTail
OrganismPatagioenas fasciata monilis
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Patagioenas.
Aromaticity0.06
Grand average of hydropathy-0.004
Instability index48.62
Isoelectric point6.79
Molecular weight111980.36
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13124
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.81|      29|     302|     162|     209|       1
---------------------------------------------------------------------------
  130-  161 (44.78/14.26)	AEECIGLCralMSALNWLLRC....AAVYAERVKET
  167-  199 (41.03/46.20)	AESQLKLC...LERLEKMLSStknrALIHIAKLEET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     203.17|      70|     302|     556|     678|       2
---------------------------------------------------------------------------
  541-  553 (-4.27/17.65)	.................WMLTCMPEEGKIL..............................................................................................
  570-  673 (96.47/105.42)	LVALLNNSSemklvqmKWHEACLSISAAILEILNAWengvltfesiqkitdnikgkvcsmvvCAVAWLVAH....................VRMLGLDEREKSlQMIRQLATPLHSENTLQFYN
  801-  889 (110.96/54.48)	LPNLLTDSS.......KWH.TLMDPPGKALAKLSVW..........................CALSSYSSHnkgqasarqkkrhrediedyISLFPLDDTQPS.KLMRLLSSNEEDANILSSPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     332.38|     112|     453|     417|     533|       3
---------------------------------------------------------------------------
  417-  533 (170.98/146.18)	QPNPGL.ILRAEPTVTNILKTMDADHSTSpegLLGVLGHMLSGKS......LDLLLAAAAATG.KLKSFARKFIK..LNEFTKHITgEGSKGAPVRALLFDIsFLMLCHVAQTYGSEVILS...ESSPAG
  867-  991 (161.39/119.27)	QPSKLMrLLSSNEEDANILSSPNRSMSTS...LSASQLHTVSMRDplnrvlANLFLLISSILGaKTAGTHTQFVQwfMEECVDCLE.QGSRGSILQFMPFTM.VSELVKVSTMSSPRIVLAitdLSLPLG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13124 with Med24 domain of Kingdom Metazoa
Unable to open file!