<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13109

Description Uncharacterized protein
SequenceMIGLSMLQIEYNASMIVRLVEELLSVSRTLKENWILGQLPKTNEADNVDPLDGMDDKINEVLKRILHTKQFDEEVEDDESEEEEEEEEEQEPQEQQKQEQEVIPEIKSEIKVEAPSDDIMDGMITAAVDEATNEKKVEVKQEETGADSNATTEATTTNGAHDGNGGETNATNGEPEPQIPPIEDVIEIADDVLGQYDFDNFGDMGDDVNDIIMLD
Length215
PositionHead
OrganismCyberlindnera fabianii (Yeast) (Hansenula fabianii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Cyberlindnera.
Aromaticity0.03
Grand average of hydropathy-0.802
Instability index53.91
Isoelectric point4.05
Molecular weight23996.76
Publications
PubMed=28385833

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13109
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.31|      29|      82|      77|     110|       2
---------------------------------------------------------------------------
   77-  110 (38.39/26.64)	D.......DESEEEEEEEEEQEPqeQqkqEQEVIPEIKSEI
  121-  153 (26.61/ 8.93)	DgmitaavDEATNEKKVEVKQE.......ETGADSNATTE.
  162-  186 (42.32/18.08)	D.......GNGGETNATNGEPEP..Q.......IPPIEDVI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13109 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ILHTKQFDEEVEDDESEEEEEEEEEQEPQEQQKQEQEVIPEIKSEIKVEAPSDDIMDGMITAAVDEATNEKKVEVKQEETGADSNATTEATTTNGAHDGNGGETNATNGEPEPQIPPIEDVIEIADDVLGQYDFDNF
65
201










Molecular Recognition Features






MoRF SequenceStartStop




1) DVNDIIMLD
2) KVEVK
3) NEVLKRILH
4) PEPQIPPIEDVIEIADDVLGQYDFDNFG
207
136
59
175
215
140
67
202