Description | mediator of RNA polymerase II transcription subunit 21-like |
Sequence | MDIISQLQEQVNSIAALTFNTFGTLQRDAPPVRLSPNYPEPPSNPTEDSANFADQPKLMSAALVKAAKQFDALVAALPPSEGGEEAQLRRIAELQAENDAVGQELQKQLEAAEKELKQVQELFSQAADNCLNLKKPD |
Length | 137 |
Position | Middle |
Organism | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.504 |
Instability index | 64.31 |
Isoelectric point | 4.48 |
Molecular weight | 14915.53 |
Publications | PubMed=25893780 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central |
GO - Biological Function | transcription coregulator activity GO:0003712 IBA:GO_Central |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central |
Binary Interactions |
Repeats | >MDP13065 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 74.99| 26| 27| 71| 96| 1 --------------------------------------------------------------------------- 71- 96 (42.03/23.76) DALVAALPPSEGGEEAQLRRIAEL..QA 99- 126 (32.96/17.25) DAVGQELQKQLEAAEKELKQVQELfsQA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EDSANFADQPKLMSAALVKAAKQFDALVAALPP 2) EEAQLRRIAELQAENDAVGQ 3) VRLSPNYPEPPS | 47 84 32 | 79 103 43 |
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