<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13062

Description mediator of RNA polymerase II transcription subunit 15a-like
SequenceMDTNNWRPTPPSGEPNMDSGDWRTTLQPDSRQRIVNKIMDTLKRHLPFSGQEGLSELRKIAVRFEEKIFTAASSQTDYLRRISLKMLTMETKSQNTMPNTGNNSKPPDPGSQGMQNQVHSQGQSIPIPLQSNQSQARQQLLPQSVPNNMASAGVQSSAGLQPGMPPVSGLSQNPISNVVGQNSNIQNMSGISQNSMGQGMPSNIFANQQRQMQGRQQVLPQQQQQQQQQQQQLYHQQLQQKQLSQQQQMVGSGMGPAYVQGPG
Length263
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.03
Grand average of hydropathy-0.963
Instability index75.35
Isoelectric point10.06
Molecular weight29072.15
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13062
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.42|      14|      16|     107|     121|       2
---------------------------------------------------------------------------
  107-  121 (22.91/10.24)	PDPgSQGMQNQVHSQ
  126-  139 (24.61/ 7.47)	PIP.LQSNQSQARQQ
  218-  231 (23.90/ 7.04)	VLP.QQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.53|      16|      19|     168|     185|       3
---------------------------------------------------------------------------
  168-  185 (26.55/16.47)	SGLSQNPISNvvGQNSNI
  189-  204 (31.98/15.08)	SGISQNSMGQ..GMPSNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.17|      10|      19|      57|      70|       4
---------------------------------------------------------------------------
   57-   70 (11.14/18.79)	LRKIAVrfeeKIFT
   79-   88 (17.03/11.69)	LRRISL....KMLT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13062 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDTNNWRPTPPSGEPNMDSGDWRTTLQPDSRQRIVNKIMDTLKRHLPFSGQEGLSEL
2) RRISLKMLTMETKSQNTMPNTGNNSKPPDPGSQGMQNQVHSQGQSIPIPLQSNQSQARQQLLPQSVPNNMASAGVQSSAGLQPGMPPVSGLSQNPISNVVGQNSNIQNMSGISQNSMGQGMPSNIFANQQRQMQGRQQVLPQQQQQQQQQQQQLYHQQLQQKQLSQQQQMVGSGMGPAYVQGPG
1
80
57
263










Molecular Recognition Features






MoRF SequenceStartStop




1) LYHQQL
2) PAYVQGP
3) RISLKML
233
256
81
238
262
87