<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13060
Description |
Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MDPYLGGSWTMIPSIPTHSNVSTPTNQDHLYLSPPPPSQQQHFHPQQFQQQQQQQRMLQQQQQQQQQQQVQQNQQQQSLASHFHLLHLVENLADTIDNGSRDQHSDALVNELNNHFEKCQQLLNSIAASINSKSMTVEGQKKKLEESEQLLNQRRDLIAKYRSTVEDLLKTEP |
Length | 173 |
Position | Middle |
Organism | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -1.080 |
Instability index | 57.77 |
Isoelectric point | 5.94 |
Molecular weight | 20024.88 |
Publications | PubMed=25893780
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145
|
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP13060
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 75.12| 19| 19| 39| 57| 1
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39- 57 (39.42/14.51) QQQHFHPQQFQQQQQQQRM
61- 79 (35.70/12.45) QQQQQQQQQVQQNQQQQSL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.36| 19| 32| 82| 100| 2
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82- 100 (33.21/21.61) HF.HLLHLVENLADTIDNGS
115- 134 (28.15/17.46) HFeKCQQLLNSIAASINSKS
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