<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13055

Description mediator of RNA polymerase II transcription subunit 15a-like
SequenceMHSIFQQDSLPQQPKSARLEKMKLFKTMLERILAFLTISKAAIVPAFKDKLSSYEEQIRKFRIANRPMKLVSALHQGQLLPTHMHSMQQPQPESNQTQSHDNEMNPQFPSMMRPAQMPELKKQMPRQLLQMLQQRGLHRVDEQQSPAKIKTNELSFWHEIDIDSGVQGNLPSNQLPGYKEARSEYHAPDTAGIGVPPTMSIPPLLPGFKEVNDTSGNALTTDFGKPDITEQPHDLKVNMAKPKSLSATVVTMVDEAVSAVGEDLAAMKKQGLHARNFFTQTGMSGAEKMRCYLSALVILALIIFFIFNLNHQY
Length313
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.443
Instability index47.96
Isoelectric point9.01
Molecular weight35272.36
Publications
PubMed=25893780

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
transcription coactivator activity	GO:0003713	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13055
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.94|      24|      27|     155|     180|       1
---------------------------------------------------------------------------
  155-  180 (39.22/27.68)	SFWHEIDiDSGVqGNLPSNQ....LPGYKE
  183-  210 (41.71/21.35)	SEYHAPD.TAGI.GVPPTMSipplLPGFKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.60|      18|      23|      75|      93|       2
---------------------------------------------------------------------------
   75-   93 (32.53/19.65)	HQGQLLPtHMHSMQQP..QPE
  100-  119 (33.07/15.91)	HDNEMNP.QFPSMMRPaqMPE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13055 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GVQGNLPSNQLPGYKEARSEYHAPDTAGIGVPPTM
2) LHQGQLLPTHMHSMQQPQPESNQTQSHDNEMNPQFPSMMRPAQMPELKKQMPRQLLQMLQQRGLHRVDEQQSPAKIKTNEL
165
74
199
154

Molecular Recognition Features

MoRF SequenceStartStop
NANANA